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Two-Stage Designs for Gene–Disease Association Studies with Sample Size Constraints

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  • Jaya M. Satagopan
  • E. S. Venkatraman
  • Colin B. Begg

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  • Jaya M. Satagopan & E. S. Venkatraman & Colin B. Begg, 2004. "Two-Stage Designs for Gene–Disease Association Studies with Sample Size Constraints," Biometrics, The International Biometric Society, vol. 60(3), pages 589-597, September.
  • Handle: RePEc:bla:biomet:v:60:y:2004:i:3:p:589-597
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    File URL: http://hdl.handle.net/10.1111/j.0006-341X.2004.00207.x
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    References listed on IDEAS

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    1. Neil J. Risch, 2000. "Searching for genetic determinants in the new millennium," Nature, Nature, vol. 405(6788), pages 847-856, June.
    2. Jaya M. Satagopan & David A. Verbel & E. S. Venkatraman & Kenneth E. Offit & Colin B. Begg, 2002. "Two-Stage Designs for Gene–Disease Association Studies," Biometrics, The International Biometric Society, vol. 58(1), pages 163-170, March.
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    Cited by:

    1. Sato Yasunori & Laird Nan & Suganami Hideki & Hamada Chikuma & Niki Naoto & Yoshimura Isao & Yoshida Teruhiko, 2009. "Statistical Screening Method for Genetic Factors Influencing Susceptibility to Common Diseases in a Two-Stage Genome-Wide Association Study," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 8(1), pages 1-21, November.
    2. André Scherag & Johannes Hebebrand & Helmut Schäfer & Hans-Helge Müller, 2009. "Flexible Designs for Genomewide Association Studies," Biometrics, The International Biometric Society, vol. 65(3), pages 815-821, September.
    3. T. Tony Cai & Wenguang Sun, 2017. "Optimal screening and discovery of sparse signals with applications to multistage high throughput studies," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 79(1), pages 197-223, January.
    4. Duncan C. Thomas, 2005. "Discussion on "Statistical Issues Arising in the Women's Health Initiative"," Biometrics, The International Biometric Society, vol. 61(4), pages 930-933, December.
    5. Steibel, Juan P. & Rosa, Guilherme J.M. & Tempelman, Robert J., 2009. "Optimizing design of two-stage experiments for transcriptional profiling," Computational Statistics & Data Analysis, Elsevier, vol. 53(5), pages 1639-1649, March.
    6. József Bukszár & Edwin J. C. G. van den Oord, 2006. "Optimization of Two-Stage Genetic Designs Where Data Are Combined Using an Accurate and Efficient Approximation for Pearson's Statistic," Biometrics, The International Biometric Society, vol. 62(4), pages 1132-1137, December.
    7. Minjung Kwak & Jungnam Joo & Gang Zheng, 2009. "A Robust Test for Two-Stage Design in Genome-Wide Association Studies," Biometrics, The International Biometric Society, vol. 65(4), pages 1288-1295, December.

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