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Effects of physical activity on cognitive functioning in middle age: Evidence from the whitehall II prospective cohort study

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  • Singh-Manoux, A.
  • Hillsdon, M.
  • Brunner, E.
  • Marmot, M.

Abstract

Objectives. We examined the association between physical activity and cognitive functioning in middle age. Methods. Data were derived from a prospective occupational cohort study of 10308 civil servants aged 35-55 years at baseline (phase 1; 1985-1988). Physical activity level, categorized as low, medium, or high, was assessed at phases 1, 3 (1991-1994), and 5 (1997-1999). Cognitive functioning was tested at phase 5, when respondents were 46-68 years old. Results. In both prospective (odds ratio [OR] = 1.65; 95% confidence interval [CI] = 1.30, 2.10) and cross-sectional (OR = 1.79; 95% CI = 1.38, 2.32) analyses, low levels of physical activity were a risk factor for poor performance on a measure of fluid intelligence. Analyses aimed at assessing cumulative effects (summary of physical activity levels at the 3 time points) showed a graded linear relationship with fluid intelligence, with persistently low levels of physical activity being particularly harmful (OR = 2.21; 95% CI = 1.37, 3.57). Conclusions. Low levels of physical activity are a risk factor for cognitive functioning in middle age, fluid intelligence in particular.

Suggested Citation

  • Singh-Manoux, A. & Hillsdon, M. & Brunner, E. & Marmot, M., 2005. "Effects of physical activity on cognitive functioning in middle age: Evidence from the whitehall II prospective cohort study," American Journal of Public Health, American Public Health Association, vol. 95(12), pages 2252-2258.
  • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2004.055574_8
    DOI: 10.2105/AJPH.2004.055574
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    Cited by:

    1. Huang, Wei & Zhou, Yi, 2013. "Effects of education on cognition at older ages: Evidence from China's Great Famine," Social Science & Medicine, Elsevier, vol. 98(C), pages 54-62.
    2. Yiping Yang & Le Sun & Buxin Han & Pingping Liu, 2023. "The Trajectory of Anthropomorphism and Pro-Environmental Behavior: A Serial Mediation Model," IJERPH, MDPI, vol. 20(3), pages 1-19, January.
    3. Taehyun Ahn & Kyong Duk Choi, 2019. "Grandparent caregiving and cognitive functioning among older people: evidence from Korea," Review of Economics of the Household, Springer, vol. 17(2), pages 553-586, June.
    4. Lenzen, Sabrina & Gannon, Brenda & Rose, Christiern, 2020. "A dynamic microeconomic analysis of the impact of physical activity on cognition among older people," Economics & Human Biology, Elsevier, vol. 39(C).
    5. Dylan B. Jackson & Kevin M. Beaver, 2015. "The Role of Adolescent Nutrition and Physical Activity in the Prediction of Verbal Intelligence during Early Adulthood: A Genetically Informed Analysis of Twin Pairs," IJERPH, MDPI, vol. 12(1), pages 1-17, January.
    6. Daugherty, Ana M. & Zwilling, Christopher & Paul, Erick J. & Sherepa, Nikolai & Allen, Courtney & Kramer, Arthur F. & Hillman, Charles H. & Cohen, Neal J. & Barbey, Aron K., 2018. "Multi-modal fitness and cognitive training to enhance fluid intelligence," Intelligence, Elsevier, vol. 66(C), pages 32-43.

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