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Estimation of genetic parameters using molecular markers and EM-algorithms

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  • Emrich, Katharina
  • Wolfgang, Urfer

Abstract

In this paper we present a new method for estimating genetic parameters of an F2- generation model. Using an iterative algorithm we derive explicit expressions for the Maximum Likelihood estimates of the additive and dominance effects. Finally we calculate the variance covariance matrix of our Maximum Likelihood estimates, which enables us to determine a confidence interval for the location of a quantitative trait locus.

Suggested Citation

  • Emrich, Katharina & Wolfgang, Urfer, 1999. "Estimation of genetic parameters using molecular markers and EM-algorithms," Technical Reports 1999,48, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    • Handle: RePEc:zbw:sfb475:199948
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    References listed on IDEAS

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    1. Urfer, Wolfgang & Mejza, S. & Hering, F., 1999. "Quantitative trait loci mapping in plant genetics by [alpha]-design experiments and molecular genetic marker systems," Technical Reports 1999,34, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
    2. Selinski, Silvia & Urfer, Wolfgang, 1998. "Interindividual and interoccasion variability of toxicokinetic parameters in population models," Technical Reports 1998,38, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
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