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Exploring the Antibiotics Innovation System and R&D policies in China: Mission Oriented Innovation?

Author

Listed:
  • Yuhan Bao

    (School of Public Policy and Management, Tsinghua University. China)

  • Adrian Ely

    (Science Policy Research Unit, University of Sussex Business School, Falmer, Brighton, UK)

  • Michael M. Hopkins

    (Science Policy Research Unit, University of Sussex Business School, Falmer, Brighton, UK)

  • Xianzhe Li

    (School of Public Health, Peking University, China)

  • Yangmu Huang

    (School of Public Health, Peking University, China)

Abstract

One possible response to the growing problem of Antimicrobial Resistance (AMR) in pathogenic infections is the development of new types of antibiotics. However, the pharmaceutical companies that have traditionally led such innovation face a lack of incentives at the present time due to high levels of market uncertainty and low expected returns. Mission oriented innovation with coordinated investment and market-shaping policies may offer an approach to accelerating antibiotic innovation. This paper aims to evaluate whether preCovid-19 Chinese policies concerning AMR can be seen as constituting a mission-oriented approach and whether these policies have influenced antibiotics innovation in China. It adopts a mixed method approach to deliver several insights. By using historical event analysis based on data collected from interviews, public and commercial databases as well as policy documents, the paper finds that China’s recent actions concerning AMR since 2008 comprise many elements of mission-oriented innovation policy. The National Action Plan to Contain AMR has provided a clear mission since 2016 to tackle the problem of AMR and provides the opportunity to coordinate and integrate these policies into a more coherent and evolving mission-oriented innovation approach. Analysis of relevant research grants and publications suggest that these policies (including the 2016 National Action Plan) have drawn the scientific community towards antibiotics research and provided more support to this area. Case studies following the development of new antibiotics are used to illustrate how the established elements of mission oriented innovation policy have or have not contributed to antibiotics innovation in China. Further research is required to more comprehensively analyse R&D investments, and to understand the effects of recent policies, especially after 2016.

Suggested Citation

  • Yuhan Bao & Adrian Ely & Michael M. Hopkins & Xianzhe Li & Yangmu Huang, 2021. "Exploring the Antibiotics Innovation System and R&D policies in China: Mission Oriented Innovation?," SPRU Working Paper Series 2021-04, SPRU - Science Policy Research Unit, University of Sussex Business School.
    • Handle: RePEc:sru:ssewps:2021-04
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    References listed on IDEAS

    as
    1. Mariana Mazzucato, 2018. "Mission-oriented innovation policies: challenges and opportunities," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 27(5), pages 803-815.
    2. Weber, K. Matthias & Rohracher, Harald, 2012. "Legitimizing research, technology and innovation policies for transformative change," Research Policy, Elsevier, vol. 41(6), pages 1037-1047.
    3. Sampat, Bhaven N., 2012. "Mission-oriented biomedical research at the NIH," Research Policy, Elsevier, vol. 41(10), pages 1729-1741.
    4. Mariana Mazzucato & Caetano C.R. Penna, 2016. "Beyond market failures: the market creating and shaping roles of state investment banks," Journal of Economic Policy Reform, Taylor and Francis Journals, vol. 19(4), pages 305-326, October.
    5. Mariana Mazzucato, 2016. "From market fixing to market-creating: a new framework for innovation policy," Industry and Innovation, Taylor & Francis Journals, vol. 23(2), pages 140-156, February.
    6. Mowery, David C., 2012. "Defense-related R&D as a model for “Grand Challenges” technology policies," Research Policy, Elsevier, vol. 41(10), pages 1703-1715.
    7. Kevin R Foster & Hajo Grundmann, 2006. "Do We Need to Put Society First? The Potential for Tragedy in Antimicrobial Resistance," PLOS Medicine, Public Library of Science, vol. 3(2), pages 1-1, January.
    8. Mariana Mazzucato & Caetano C.R. Penna, 2016. "Beyond market failures: the market creating and shaping roles of state investment banks," Journal of Economic Policy Reform, Taylor & Francis Journals, vol. 19(4), pages 305-326, October.
    9. Gotham, Dzintars & Moja, Lorenzo & van der Heijden, Maarten & Paulin, Sarah & Smith, Ingrid & Beyer, Peter, 2021. "Reimbursement models to tackle market failures for antimicrobials: Approaches taken in France, Germany, Sweden, the United Kingdom, and the United States," Health Policy, Elsevier, vol. 125(3), pages 296-306.
    10. Foray, D. & Mowery, D.C. & Nelson, R.R., 2012. "Public R&D and social challenges: What lessons from mission R&D programs?," Research Policy, Elsevier, vol. 41(10), pages 1697-1702.
    11. Schot, Johan & Steinmueller, W. Edward, 2018. "Three frames for innovation policy: R&D, systems of innovation and transformative change," Research Policy, Elsevier, vol. 47(9), pages 1554-1567.
    12. Rainer Kattel & Mariana Mazzucato, 2018. "Mission-oriented innovation policy and dynamic capabilities in the public sector," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 27(5), pages 787-801.
    13. Rosenberg, Nathan, 1969. "The Direction of Technological Change: Inducement Mechanisms and Focusing Devices," Economic Development and Cultural Change, University of Chicago Press, vol. 18(1), pages 1-24, Part I Oc.
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    Keywords

    Antimicrobial Resistance; mission-oriented innovation; National S&T major research project; market shaping policy;
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