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Restoration of Monotonicity Respecting in Dynamic Regression

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  • Yijian Huang

Abstract

Dynamic regression models, including the quantile regression model and Aalen’s additive hazards model, are widely adopted to investigate evolving covariate effects. Yet lack of monotonicity respecting with standard estimation procedures remains an outstanding issue. Advances have recently been made, but none provides a complete resolution. In this article, we propose a novel adaptive interpolation method to restore monotonicity respecting, by successively identifying and then interpolating nearest monotonicity-respecting points of an original estimator. Under mild regularity conditions, the resulting regression coefficient estimator is shown to be asymptotically equivalent to the original. Our numerical studies have demonstrated that the proposed estimator is much more smooth and may have better finite-sample efficiency than the original as well as, when available as only in special cases, other competing monotonicity-respecting estimators. Illustration with a clinical study is provided.

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  • Yijian Huang, 2017. "Restoration of Monotonicity Respecting in Dynamic Regression," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(518), pages 613-622, April.
    • Handle: RePEc:taf:jnlasa:v:112:y:2017:i:518:p:613-622
    DOI: 10.1080/01621459.2016.1149070
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    1. J. E. Soh & Yijian Huang, 2021. "A varying-coefficient model for gap times between recurrent events," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(3), pages 437-459, July.
    2. Ziyi Li & Yijian Huang & Dattatraya Patil & Martin G. Sanda, 2023. "Covariate adjustment in continuous biomarker assessment," Biometrics, The International Biometric Society, vol. 79(1), pages 39-48, March.

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