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Evaluating the Generalisability of Trial Results: Introducing a Centre- and Trial-Level Generalisability Index

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  • Adrian Gheorghe
  • Tracy Roberts
  • Karla Hemming
  • Melanie Calvert

Abstract

Our findings suggest that an unrepresentative selection of centres limits the external validity of trial results. The Gix may be a valuable tool to help facilitate rational selection of trial centres and ensure the generalisability of results at the jurisdiction level. Copyright Springer International Publishing Switzerland 2015

Suggested Citation

  • Adrian Gheorghe & Tracy Roberts & Karla Hemming & Melanie Calvert, 2015. "Evaluating the Generalisability of Trial Results: Introducing a Centre- and Trial-Level Generalisability Index," PharmacoEconomics, Springer, vol. 33(11), pages 1195-1214, November.
  • Handle: RePEc:spr:pharme:v:33:y:2015:i:11:p:1195-1214
    DOI: 10.1007/s40273-015-0298-3
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    1. Nils Gutacker & Chris Bojke & Silvio Daidone & Nancy J. Devlin & David Parkin & Andrew Street, 2013. "Truly Inefficient Or Providing Better Quality Of Care? Analysing The Relationship Between Risk‐Adjusted Hospital Costs And Patients' Health Outcomes," Health Economics, John Wiley & Sons, Ltd., vol. 22(8), pages 931-947, August.
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