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The association of unemployment with glucose metabolism: a systematic review and meta-analysis

Author

Listed:
  • Tuulia Varanka-Ruuska

    (University of Oulu
    Kallio Primary Health Care Unit)

  • Nina Rautio

    (University of Oulu
    Oulu University Hospital)

  • Heli Lehtiniemi

    (University of Oulu)

  • Jouko Miettunen

    (University of Oulu
    Oulu University Hospital and University of Oulu)

  • Sirkka Keinänen-Kiukaanniemi

    (University of Oulu
    Oulu University Hospital
    Oulu University Hospital and University of Oulu
    Health Center of Oulu)

  • Sylvain Sebert

    (University of Oulu
    University of Oulu
    Imperial College London)

  • Leena Ala-Mursula

    (University of Oulu)

Abstract

Objectives Unemployment has been linked with poor health. We hypothesized that being unemployed is associated with disorders of glucose metabolism and performed a systematic review and meta-analysis of the literature to ascertain the relationship. Methods We searched the databases of Scopus, Medline Ovid and Web of Science for population-based original studies for past 20 years. Random effects meta-analyses were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for prediabetes and type 2 diabetes among the unemployed as compared to those employed, separately for men and women when possible. Results Out of 981 articles found, 12 articles were included in the systematic review and eight articles in the meta-analyses. Unemployment was associated with 1.6-fold odds for prediabetes (OR 1.58; 95% CI 1.07–2.35), and 1.7-fold odds for type 2 diabetes (OR 1.72; 95% CI 1.14–2.58) in the total sample. The corresponding associations for type 2 diabetes were also found stratified for men (OR 1.53; 95% CI 1.47–1.60) and women (OR 1.60; 95% CI 1.33–1.92). Conclusions Unemployment is associated with prediabetes and type 2 diabetes, global concerns of public health with potential for prevention.

Suggested Citation

  • Tuulia Varanka-Ruuska & Nina Rautio & Heli Lehtiniemi & Jouko Miettunen & Sirkka Keinänen-Kiukaanniemi & Sylvain Sebert & Leena Ala-Mursula, 2018. "The association of unemployment with glucose metabolism: a systematic review and meta-analysis," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 63(4), pages 435-446, May.
    • Handle: RePEc:spr:ijphth:v:63:y:2018:i:4:d:10.1007_s00038-017-1040-z
    DOI: 10.1007/s00038-017-1040-z
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    References listed on IDEAS

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