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Patients' Utilities for Cancer Treatments

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  • Sylvia J.T. Jansen
  • Anne M. Stiggelbout
  • Peter P. Wakker
  • Thea P.M. Vliet Vlieland
  • Jan-Willem H. Leer
  • Marianne A. Nooy
  • Job Kievit

Abstract

Objective. Temporary health states cannot be measured in the traditional way by means of techniques such as the time tradeoff (TTO) and the standard gamble (SG), where health states are chronic and are followed by death. Chained methods have been developed to solve this problem. This study assesses the feasibility of a chained TTO and a chained SG, and the consistency and concordance between the two meth ods. Patients and methods. Seventy female early-stage breast cancer patients were interviewed. In using both chained methods, the temporary health state to be evaluated was weighed indirectly with the aid of a temporary anchor health state. The patients were asked to evaluate their actual health states, a hypothetical radiotherapy scenario, and a hypothetical chemotherapy scenario. Results. Sixty-eight patients completed the interview. The use of the anchor health state yielded some problems. A significant difference between the means of the TTO and the SG was found for the anchor health state only. For the other health states, the results were remarkably close, because the design avoided some of the bias effects in traditional measurements. Conclusion. The feasibility and the consistency of the chained procedure were satisfactory for both methods. The problems regarding the anchor health state can be solved by adapting the methods and by the use of a carefully chosen anchor health state. The chained method avoids biases present in the conventional method, and thereby the TTO and the SG may be reconciled. Moreover, there are several psychological advantages to the method, which makes it useful for diseases with uncertain prognoses. Key words: utility assessment; time tradeoff; standard gamble; breast cancer; chemotherapy; ra diotherapy. (Med Decis Making 1998;18:391-399)

Suggested Citation

  • Sylvia J.T. Jansen & Anne M. Stiggelbout & Peter P. Wakker & Thea P.M. Vliet Vlieland & Jan-Willem H. Leer & Marianne A. Nooy & Job Kievit, 1998. "Patients' Utilities for Cancer Treatments," Medical Decision Making, , vol. 18(4), pages 391-399, October.
    • Handle: RePEc:sae:medema:v:18:y:1998:i:4:p:391-399
    DOI: 10.1177/0272989X9801800406
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    References listed on IDEAS

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    1. K Bennett & G Torrance & R Guscott & L Moran, 1996. "McSAD Mental Health State Utilities: Results of a Survey in Major, Unipolar Depression," Centre for Health Economics and Policy Analysis Working Paper Series 1996-20, Centre for Health Economics and Policy Analysis (CHEPA), McMaster University, Hamilton, Canada.
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    Cited by:

    1. Bromley, Hannah L. & Petrie, Dennis & Mann, G.Bruce & Nickson, Carolyn & Rea, Daniel & Roberts, Tracy E., 2019. "Valuing the health states associated with breast cancer screening programmes: A systematic review of economic measures," Social Science & Medicine, Elsevier, vol. 228(C), pages 142-154.
    2. Anne Spencer, 2001. "The Implications of Linking Questions within the SG and TTO Methods," Working Papers 438, Queen Mary University of London, School of Economics and Finance.
    3. Anne Spencer, 2001. "The Time Trade-Off Method: An Exploratory Study," Working Papers 437, Queen Mary University of London, School of Economics and Finance.
    4. Anne Spencer, 2001. "The Time Trade-Off Method: An Exploratory Study," Working Papers 437, Queen Mary University of London, School of Economics and Finance.
    5. Paul McNamee & Sharon Glendinning & Jonathan Shenfine & Nick Steen & S. Griffin & John Bond, 2004. "Chained time trade-off and standard gamble methods," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 5(1), pages 81-86, February.
    6. Joshua A. Salomon & Christopher J.L. Murray, 2004. "A multi‐method approach to measuring health‐state valuations," Health Economics, John Wiley & Sons, Ltd., vol. 13(3), pages 281-290, March.
    7. Mohan V. Bala & Gary A. Zarkin, 2000. "Are QALYs an appropriate measure for valuing morbidity in acute diseases?," Health Economics, John Wiley & Sons, Ltd., vol. 9(2), pages 177-180, March.
    8. Anne Spencer, 2001. "The Implications of Linking Questions within the SG and TTO Methods," Working Papers 438, Queen Mary University of London, School of Economics and Finance.
    9. Anne Spencer, 2004. "The implications of linking questions within the SG and TTO methods," Health Economics, John Wiley & Sons, Ltd., vol. 13(8), pages 807-818, August.
    10. Peasgood, T & Ward, S & Brazier, J, 2010. "A review and meta-analysis of health state utility values in breast cancer," MPRA Paper 29950, University Library of Munich, Germany.
    11. Anne Spencer, 2003. "The TTO method and procedural invariance," Health Economics, John Wiley & Sons, Ltd., vol. 12(8), pages 655-668, August.

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