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ShenQi FuZheng Injection combined with chemotherapy in the treatment of colorectal cancer: A meta-analysis

Author

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  • Rongzhong Xu
  • Liubing Lin
  • Yong Li
  • Yan Li

Abstract

Objective: This study aims to investigate cellular immunity and clinical efficacy of ShenQi FuZheng Injection (SFI) in the associated chemotherapy of colorectal cancer (CRC). Methods: PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Full-text Database (VIP), WanFang Database and Chinese Biomedical Literature Database (CBM) searches were undertaken to identify randomized controlled trials of SFI plus chemotherapy versus chemotherapy alone in CRC patients. The quality of each trial was assessed according to the Jadad’s scale, and Review Manager 5 was used to statisitically analyze the outcomes. Results: Eight studies involving 722 patients were included in this review. The meta-analyses suggested there was a significantly higher overall response rate (OR 1.89; CI: 1.10–3.24; p = 0.02), grades of KPS (OR 2.35; CI: 1.55–3.56; p

Suggested Citation

  • Rongzhong Xu & Liubing Lin & Yong Li & Yan Li, 2017. "ShenQi FuZheng Injection combined with chemotherapy in the treatment of colorectal cancer: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-13, September.
    • Handle: RePEc:plo:pone00:0185254
    DOI: 10.1371/journal.pone.0185254
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    References listed on IDEAS

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    1. A. E. Ades & G. Lu & J. P. T. Higgins, 2005. "The Interpretation of Random-Effects Meta-Analysis in Decision Models," Medical Decision Making, , vol. 25(6), pages 646-654, November.
    2. Cao dedong & Xu huilin & He Anbing & Xu Ximing & Ge wei, 2016. "The Effect of ShenQi FuZheng Injection in Combination with Chemotherapy versus Chemotherapy Alone on the Improvement of Efficacy and Immune Function in Patients with Advanced Non-Small Cell Lung Cance," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-16, March.
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