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Effect of Noise in Intelligent Cellular Decision Making

Author

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  • Russell Bates
  • Oleg Blyuss
  • Ahmed Alsaedi
  • Alexey Zaikin

Abstract

Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons, simple intelligent schemes known from studies on Artificial Intelligence. We study the role of genetic noise in intelligent decision making at the genetic level and show that noise can play a constructive role helping cells to make a proper decision. We show this using the example of a simple genetic classifier able to classify two external stimuli.

Suggested Citation

  • Russell Bates & Oleg Blyuss & Ahmed Alsaedi & Alexey Zaikin, 2015. "Effect of Noise in Intelligent Cellular Decision Making," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-16, May.
    • Handle: RePEc:plo:pone00:0125079
    DOI: 10.1371/journal.pone.0125079
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    References listed on IDEAS

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    1. Lulu Qian & Erik Winfree & Jehoshua Bruck, 2011. "Neural network computation with DNA strand displacement cascades," Nature, Nature, vol. 475(7356), pages 368-372, July.
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