IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v586y2020i7831d10.1038_s41586-020-2817-4.html
   My bibliography  Save this article

Strategic vision for improving human health at The Forefront of Genomics

Author

Listed:
  • Eric D. Green

    (National Institutes of Health)

  • Chris Gunter

    (National Institutes of Health)

  • Leslie G. Biesecker

    (National Institutes of Health)

  • Valentina Francesco

    (National Institutes of Health)

  • Carla L. Easter

    (National Institutes of Health)

  • Elise A. Feingold

    (National Institutes of Health)

  • Adam L. Felsenfeld

    (National Institutes of Health)

  • David J. Kaufman

    (National Institutes of Health)

  • Elaine A. Ostrander

    (National Institutes of Health)

  • William J. Pavan

    (National Institutes of Health)

  • Adam M. Phillippy

    (National Institutes of Health)

  • Anastasia L. Wise

    (National Institutes of Health)

  • Jyoti Gupta Dayal

    (National Institutes of Health)

  • Britny J. Kish

    (National Institutes of Health)

  • Allison Mandich

    (National Institutes of Health)

  • Christopher R. Wellington

    (National Institutes of Health)

  • Kris A. Wetterstrand

    (National Institutes of Health)

  • Sarah A. Bates

    (National Institutes of Health)

  • Darryl Leja

    (National Institutes of Health)

  • Susan Vasquez

    (National Institutes of Health)

  • William A. Gahl

    (National Institutes of Health)

  • Bettie J. Graham

    (National Institutes of Health)

  • Daniel L. Kastner

    (National Institutes of Health)

  • Paul Liu

    (National Institutes of Health)

  • Laura Lyman Rodriguez

    (National Institutes of Health)

  • Benjamin D. Solomon

    (National Institutes of Health)

  • Vence L. Bonham

    (National Institutes of Health)

  • Lawrence C. Brody

    (National Institutes of Health)

  • Carolyn M. Hutter

    (National Institutes of Health)

  • Teri A. Manolio

    (National Institutes of Health)

Abstract

Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to identify future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we describe the highest-priority elements envisioned for the cutting-edge of human genomics going forward—that is, at ‘The Forefront of Genomics’.

Suggested Citation

  • Eric D. Green & Chris Gunter & Leslie G. Biesecker & Valentina Francesco & Carla L. Easter & Elise A. Feingold & Adam L. Felsenfeld & David J. Kaufman & Elaine A. Ostrander & William J. Pavan & Adam M, 2020. "Strategic vision for improving human health at The Forefront of Genomics," Nature, Nature, vol. 586(7831), pages 683-692, October.
    • Handle: RePEc:nat:nature:v:586:y:2020:i:7831:d:10.1038_s41586-020-2817-4
    DOI: 10.1038/s41586-020-2817-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41586-020-2817-4
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/s41586-020-2817-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Lama AlAbdi & Sateesh Maddirevula & Hanan E. Shamseldin & Ebtissal Khouj & Rana Helaby & Halima Hamid & Aisha Almulhim & Mais O. Hashem & Firdous Abdulwahab & Omar Abouyousef & Mashael Alqahtani & Nor, 2023. "Diagnostic implications of pitfalls in causal variant identification based on 4577 molecularly characterized families," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    2. Amartya Mukhopadhyay & Jennifer Sumner & Lieng Hsi Ling & Raphael Hao Chong Quek & Andre Teck Huat Tan & Gim Gee Teng & Santhosh Kumar Seetharaman & Satya Pavan Kumar Gollamudi & Dean Ho & Mehul Motan, 2022. "Personalised Dosing Using the CURATE.AI Algorithm: Protocol for a Feasibility Study in Patients with Hypertension and Type II Diabetes Mellitus," IJERPH, MDPI, vol. 19(15), pages 1-11, July.
    3. Shim, Janet K. & Bentz, Michael & Vasquez, Emily & Jeske, Melanie & Saperstein, Aliya & Fullerton, Stephanie M. & Foti, Nicole & McMahon, Caitlin & Lee, Sandra Soo-Jin, 2022. "Strategies of inclusion: The tradeoffs of pursuing “baked in” diversity through place-based recruitment," Social Science & Medicine, Elsevier, vol. 306(C).
    4. Manuela Priolo & Marco Tartaglia, 2023. "The Right to Ask, the Need to Answer—When Patients Meet Research: How to Cope with Time," IJERPH, MDPI, vol. 20(5), pages 1-10, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:586:y:2020:i:7831:d:10.1038_s41586-020-2817-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.