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Auditory cortex conveys non-topographic sound localization signals to visual cortex

Author

Listed:
  • Camille Mazo

    (Champalimaud Foundation)

  • Margarida Baeta

    (Champalimaud Foundation)

  • Leopoldo Petreanu

    (Champalimaud Foundation)

Abstract

Spatiotemporally congruent sensory stimuli are fused into a unified percept. The auditory cortex (AC) sends projections to the primary visual cortex (V1), which could provide signals for binding spatially corresponding audio-visual stimuli. However, whether AC inputs in V1 encode sound location remains unknown. Using two-photon axonal calcium imaging and a speaker array, we measured the auditory spatial information transmitted from AC to layer 1 of V1. AC conveys information about the location of ipsilateral and contralateral sound sources to V1. Sound location could be accurately decoded by sampling AC axons in V1, providing a substrate for making location-specific audiovisual associations. However, AC inputs were not retinotopically arranged in V1, and audio-visual modulations of V1 neurons did not depend on the spatial congruency of the sound and light stimuli. The non-topographic sound localization signals provided by AC might allow the association of specific audiovisual spatial patterns in V1 neurons.

Suggested Citation

  • Camille Mazo & Margarida Baeta & Leopoldo Petreanu, 2024. "Auditory cortex conveys non-topographic sound localization signals to visual cortex," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-47546-4
    DOI: 10.1038/s41467-024-47546-4
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    References listed on IDEAS

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