IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i5p4146-d1080450.html
   My bibliography  Save this article

Suicide Mortality Risk among Patients with Lung Cancer—A Systematic Review and Meta-Analysis

Author

Listed:
  • Luisa Hofmann

    (Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Nußbaumstraße 7, 80336 Munich, Germany
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitätsstraße 84, 93053 Regensburg, Germany)

  • Michael Heinrich

    (Faculty of Medicine, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany)

  • Hansjörg Baurecht

    (Department of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany)

  • Berthold Langguth

    (Department of Psychiatry and Psychotherapy, University of Regensburg, Universitätsstraße 84, 93053 Regensburg, Germany)

  • Peter M. Kreuzer

    (Department of Psychiatry and Psychotherapy, University of Regensburg, Universitätsstraße 84, 93053 Regensburg, Germany)

  • Helge Knüttel

    (University Library, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany)

  • Michael F. Leitzmann

    (Department of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany)

  • Corinna Seliger

    (Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany)

Abstract

The risk for suicide in patients with cancer is higher compared to the general population. However, little is known about patients with lung cancer specifically. We therefore implemented a systematic review and random-effects meta-analysis of retrospective cohort studies on suicide in patients with lung cancer. We searched a high number of common databases up to 02/2021. For the systematic review, a total of 23 studies was included. To exclude bias due to patient sample overlap, the meta-analysis was performed on 12 studies. The pooled standardized mortality ratio (SMR) for suicide was 2.95 (95% Confidence Interval (CI) = 2.42–3.60) for patients with lung cancer as compared to the general population. Subgroups with a pronouncedly higher risk for suicide compared to the general population were found for patients living in the USA (SMR = 4.17, 95% CI = 3.88–4.48), with tumors of late stage (SMR = 4.68, 95% CI = 1.28–17.14), and within one year after diagnosis (SMR = 5.00, 95% CI = 4.11–6.08). An increased risk for suicide was found in patients with lung cancer, with subgroups at particular risk. Patients at increased risk should be monitored more closely for suicidality and should receive specialized psycho-oncological and psychiatric care. Further studies should clarify the role of smoking and depressive symptoms on suicidality among lung cancer patients.

Suggested Citation

  • Luisa Hofmann & Michael Heinrich & Hansjörg Baurecht & Berthold Langguth & Peter M. Kreuzer & Helge Knüttel & Michael F. Leitzmann & Corinna Seliger, 2023. "Suicide Mortality Risk among Patients with Lung Cancer—A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(5), pages 1-15, February.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:5:p:4146-:d:1080450
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/5/4146/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/5/4146/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. T. D. Stanley, 1998. "New Wine in Old Bottles: A Meta‐Analysis of Ricardian Equivalence," Southern Economic Journal, John Wiley & Sons, vol. 64(3), pages 713-727, January.
    2. Tomáš Havránek, 2015. "Measuring Intertemporal Substitution: The Importance Of Method Choices And Selective Reporting," Journal of the European Economic Association, European Economic Association, vol. 13(6), pages 1180-1204, December.
    3. Nolte, Ellen & McKee, Martin, 2011. "Variations in amenable mortality—Trends in 16 high-income nations," Health Policy, Elsevier, vol. 103(1), pages 47-52.
    4. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    5. Marija Milic & Tatjana Gazibara & Tatjana Pekmezovic & Darija Kisic Tepavcevic & Gorica Maric & Aleksandra Popovic & Jasmina Stevanovic & Karamchand Hukumchand Patil & Hagai Levine, 2020. "Tobacco smoking and health-related quality of life among university students: Mediating effect of depression," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-18, January.
    6. Viechtbauer, Wolfgang, 2010. "Conducting Meta-Analyses in R with the metafor Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 36(i03).
    7. Justin van der Sluis & Mirjam van Praag & Wim Vijverberg, 2005. "Entrepreneurship Selection and Performance: A Meta-Analysis of the Impact of Education in Developing Economies," The World Bank Economic Review, World Bank, vol. 19(2), pages 225-261.
    8. Nicholas G. Zaorsky & Ying Zhang & Leonard Tuanquin & Shirley M. Bluethmann & Henry S. Park & Vernon M. Chinchilli, 2019. "Suicide among cancer patients," Nature Communications, Nature, vol. 10(1), pages 1-7, December.
    9. Hui-Chu Lang & Shi-Liang Wu, 2012. "Lifetime costs of the top five cancers in Taiwan," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 13(3), pages 347-353, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Piers Steel & Sjoerd Beugelsdijk & Herman Aguinis, 2021. "The anatomy of an award-winning meta-analysis: Recommendations for authors, reviewers, and readers of meta-analytic reviews," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 52(1), pages 23-44, February.
    2. Gechert, Sebastian & Heimberger, Philipp, 2022. "Do corporate tax cuts boost economic growth?," European Economic Review, Elsevier, vol. 147(C).
    3. Mahesh Shumsher Rughooputh & Rui Zeng & Ying Yao, 2015. "Protein Diet Restriction Slows Chronic Kidney Disease Progression in Non-Diabetic and in Type 1 Diabetic Patients, but Not in Type 2 Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials ," PLOS ONE, Public Library of Science, vol. 10(12), pages 1-17, December.
    4. Christopher Winchester & Kelsey E. Medeiros, 2023. "In Bounds but Out of the Box: A Meta-Analysis Clarifying the Effect of Ethicality on Creativity," Journal of Business Ethics, Springer, vol. 183(3), pages 713-743, March.
    5. Kelly R Moran & Sara Y Del Valle, 2016. "A Meta-Analysis of the Association between Gender and Protective Behaviors in Response to Respiratory Epidemics and Pandemics," PLOS ONE, Public Library of Science, vol. 11(10), pages 1-25, October.
    6. Sandra Feijóo & Raquel Rodríguez-Fernández, 2021. "A Meta-Analytical Review of Gender-Based School Bullying in Spain," IJERPH, MDPI, vol. 18(23), pages 1-13, December.
    7. Xizheng Xu & Zhiqiang Liu & Shaoying Gong & Yunpeng Wu, 2022. "The Relationship between Empathy and Attachment in Children and Adolescents: Three-Level Meta-Analyses," IJERPH, MDPI, vol. 19(3), pages 1-18, January.
    8. Kathrin Wunsch & Janis Fiedler & Philip Bachert & Alexander Woll, 2021. "The Tridirectional Relationship among Physical Activity, Stress, and Academic Performance in University Students: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(2), pages 1-18, January.
    9. Alan da Silveira Fleck & Margaux L. Sadoine & Stéphane Buteau & Eva Suarthana & Maximilien Debia & Audrey Smargiassi, 2021. "Environmental and Occupational Short-Term Exposure to Airborne Particles and FEV 1 and FVC in Healthy Adults: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(20), pages 1-19, October.
    10. Evangelos Danopoulos & Maureen Twiddy & Jeanette M Rotchell, 2020. "Microplastic contamination of drinking water: A systematic review," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-23, July.
    11. Claudia Menne-Lothmann & Wolfgang Viechtbauer & Petra Höhn & Zuzana Kasanova & Simone P Haller & Marjan Drukker & Jim van Os & Marieke Wichers & Jennifer Y F Lau, 2014. "How to Boost Positive Interpretations? A Meta-Analysis of the Effectiveness of Cognitive Bias Modification for Interpretation," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-26, June.
    12. Wei-Cheng Chang & Chin Lin & Cho-Hao Lee & Tzu-Ling Sung & Tao-Hsin Tung & Jorn-Hon Liu, 2017. "Vitrectomy with or without internal limiting membrane peeling for idiopathic epiretinal membrane: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-18, June.
    13. Larkin, Matthew P. & Askarov, Zohid & Doucouliagos, Hristos & Dubelaar, Chris & Klona, Maria & Newton, Joshua & Stanley, T.D. & Vocino, Andrea, 2019. "Do house prices ride the wave of immigration?," Journal of Housing Economics, Elsevier, vol. 46(C).
    14. Christopher Hansen & Holger Steinmetz & Jörn Block, 2022. "How to conduct a meta-analysis in eight steps: a practical guide," Management Review Quarterly, Springer, vol. 72(1), pages 1-19, February.
    15. Shaylea Badovinac & Jodi Martin & Camille Guérin-Marion & Monica O’Neill & Rebecca Pillai Riddell & Jean-François Bureau & Rebecca Spiegel, 2018. "Associations between mother-preschooler attachment and maternal depression symptoms: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 13(10), pages 1-27, October.
    16. Fazel, Seena & Burghart, Matthias & Fanshawe, Thomas & Gil, Sharon Danielle & Monahan, John & Yu, Rongqin, 2022. "The predictive performance of criminal risk assessment tools used at sentencing: Systematic review of validation studies," Journal of Criminal Justice, Elsevier, vol. 81(C).
    17. Amro Qaddoura & Payam Yazdan-Ashoori & Conrad Kabali & Lehana Thabane & R Brian Haynes & Stuart J Connolly & Harriette Gillian Christine Van Spall, 2015. "Efficacy of Hospital at Home in Patients with Heart Failure: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-15, June.
    18. Boshra H. Namin & Torvald Øgaard & Jo Røislien, 2021. "Workplace Incivility and Turnover Intention in Organizations: A Meta-Analytic Review," IJERPH, MDPI, vol. 19(1), pages 1-19, December.
    19. Ruohuang Jiao & Wojtek Przepiorka & Vincent Buskens, 2022. "Moderators of reputation effects in peer-to-peer online markets: a meta-analytic model selection approach," Journal of Computational Social Science, Springer, vol. 5(1), pages 1041-1067, May.
    20. Pedro Silva Moreira & Pedro R Almeida & Hugo Leite-Almeida & Nuno Sousa & Patrício Costa, 2016. "Impact of Chronic Stress Protocols in Learning and Memory in Rodents: Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-24, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:5:p:4146-:d:1080450. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.