IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2022i1p328-d1014766.html
   My bibliography  Save this article

The TELE-DD Randomised Controlled Trial on Treatment Adherence in Patients with Type 2 Diabetes and Comorbid Depression: Clinical Outcomes after 18-Month Follow-Up

Author

Listed:
  • María Luisa Lozano del Hoyo

    (Las Fuentes Norte Health Centre, Servicio Aragonés de Salud (SALUD), 50002 Zaragoza, Spain
    Department of Physiatry and Nursing, Faculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, Spain)

  • María Teresa Fernandez Rodrigo

    (Department of Physiatry and Nursing, Faculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, Spain
    Water and Environmental Health Research Group (DGA-B43-20R), 50009 Aragón, Spain)

  • Fernando Urcola-Pardo

    (Department of Physiatry and Nursing, Faculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, Spain
    Water and Environmental Health Research Group (DGA-B43-20R), 50009 Aragón, Spain)

  • Alicia Monreal-Bartolomé

    (Aragon Institute for Health Research (IIS Aragon), 50009 Zaragoza, Spain
    Primary Care Prevention and Health Promotion Research Network, RedIAPP, 28029 Madrid, Spain)

  • Diana Cecilia Gracia Ruiz

    (Sagasta Health Center, Servicio Aragonés de Salud (SALUD), 50006 Zaragoza, Spain)

  • Mercedes Gómez Borao

    (Sagasta Health Center, Servicio Aragonés de Salud (SALUD), 50006 Zaragoza, Spain)

  • Ana Belén Artigas Alcázar

    (University Hospital Miguel Servet, Servicio Aragonés de Salud (SALUD), University of Zaragoza, 50009 Zaragoza, Spain)

  • José Pedro Martínez Casbas

    (San Pablo Health Center, Servicio Aragonés de Salud (SALUD), 50003 Zaragoza, Spain)

  • Alexandra Aceituno Casas

    (San Pablo Health Center, Servicio Aragonés de Salud (SALUD), 50003 Zaragoza, Spain)

  • María Teresa Andaluz Funcia

    (San Pablo Health Center, Servicio Aragonés de Salud (SALUD), 50003 Zaragoza, Spain)

  • Juan Francisco Roy Delgado

    (Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830 Zaragoza, Spain)

Abstract

Clinical depression is associated with poorer adherence to hypoglycaemic medication in patients with diabetes mellitus, leading to poorer glycaemic control, diabetes management, and increased complications. The main aim of the TELE-DD trial was to demonstrate the efficacy of a proactive and psychoeducational telephonic intervention based on motivational interviewing and collaborative care to reduce nonadherence and improve prognosis in individuals with diabetes mellitus and concurrent depression. Design: The TELE-DD project is a three-phased prospective study including a nested randomised controlled trial. Methods: The baseline cohort included the entire population of adult patients diagnosed with type 2 diabetes and concurrent depression. A randomised controlled trial was conducted in a selection of patients from the baseline cohort, distributed into a control group (n = 192) and an intervention group (n = 192). Monthly telephonic interventions delivered by specifically trained research nurses were centred on a psychoeducational individualised monitoring protocol including motivational interviewing and collaborative care strategies. Clinical and patient-centred data were systematically collected during an 18-month follow-up including HbA1c, Patient Health Questionnaire, and the Diabetes Distress Scale. Results: During the trial, 18-month follow-up HbA1C levels significantly ( p < 0.001) decreased in the intervention group at every follow-up from an average of 8.72 (SD:1.49) to 7.03 (SD:1.09), but slightly increased in the control group from 8.65 (SD:1.40) to 8.84 (SD:1.38). Similar positive results were obtained in depression severity and diabetes distress, LDL-cholesterol, and systolic and diastolic blood pressure, but only at the 18-month follow-up in body mass index reduction. Conclusions: This is the first trial to concurrently decrease biological and psychological outcomes with a monthly brief telephonic intervention, pointing out that a combined biopsychosocial intervention and collaborative care strategy is essential for current world health challenges. ClinicalTrials.gov Identifier: NCT04097483. Patient or Public Contribution: Diabetic patients not belonging to the TELE-DD population or trial sample were consulted during the study design to review and guarantee the clarity and understanding of the trial psychoeducational materials.

Suggested Citation

  • María Luisa Lozano del Hoyo & María Teresa Fernandez Rodrigo & Fernando Urcola-Pardo & Alicia Monreal-Bartolomé & Diana Cecilia Gracia Ruiz & Mercedes Gómez Borao & Ana Belén Artigas Alcázar & José Pe, 2022. "The TELE-DD Randomised Controlled Trial on Treatment Adherence in Patients with Type 2 Diabetes and Comorbid Depression: Clinical Outcomes after 18-Month Follow-Up," IJERPH, MDPI, vol. 20(1), pages 1-18, December.
    • Handle: RePEc:gam:jijerp:v:20:y:2022:i:1:p:328-:d:1014766
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/1/328/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/1/328/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Hayek, F. A., 2012. "Hayek on Hayek," University of Chicago Press Economics Books, University of Chicago Press, edition 1, number 9780226321202 edited by Kresge, Stephen & Wenar, Leif, September.
    2. Ewelina Cichoń & Andrzej Kiejna & Andrzej Kokoszka & Tomasz M Gondek & Rafał Radzio & Adam Jastrzębski & Beata E Andrzejewska & Fahad D Alosaimi & Cathy E Lloyd & Norman Sartorius, 2020. "People with diabetes need a lower cut-off than others for depression screening with PHQ-9," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-20, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. William R. Morgan, 2023. "Finance Must Be Defended: Cybernetics, Neoliberalism and Environmental, Social, and Governance (ESG)," Sustainability, MDPI, vol. 15(4), pages 1-21, February.
    2. Jael, Paul, 2015. "Socialist Calculation and Market Socialism," MPRA Paper 64255, University Library of Munich, Germany.
    3. Przemyslaw Zbierowski, 2015. "Positive Entrepreneurship: Antecedents and Outcomes of Entrepreneurship within Positive Organizational Scholarship (Przedsiebiorczosc pozytywna – przyczyny i rezultaty przedsiebiorczosci z zakresu poz," Problemy Zarzadzania, University of Warsaw, Faculty of Management, vol. 13(56), pages 38-54.
    4. Juan Manuel Ospina, 2019. "Economía para no economistas. Un regalo de la formación del pensamiento económico," Books, Universidad Externado de Colombia, Facultad de Ciencias Sociales y Humanas, number 136, August.
    5. Jo Michell, 2017. "Do Shadow Banks Create Money? ‘Financialisation’ and the Monetary Circuit," Metroeconomica, Wiley Blackwell, vol. 68(2), pages 354-377, May.
    6. de Ayala, Amaia & Hoyos, David & Mariel, Petr, 2015. "Suitability of discrete choice experiments for landscape management under the European Landscape Convention," Journal of Forest Economics, Elsevier, vol. 21(2), pages 79-96.
    7. Giovanna Tranfo & Lidia Caporossi & Daniela Pigini & Silvia Capanna & Bruno Papaleo & Enrico Paci, 2018. "Temporal Trends of Urinary Phthalate Concentrations in Two Populations: Effects of REACH Authorization after Five Years," IJERPH, MDPI, vol. 15(9), pages 1-13, September.
    8. Etienne Farvaque & Alexander Mihailov & Alireza Naghavi, 2018. "The Grand Experiment of Communism: Discovering the Trade-Off between Equality and Efficiency," Journal of Institutional and Theoretical Economics (JITE), Mohr Siebeck, Tübingen, vol. 174(4), pages 707-742, December.
    9. Vassiliades, C. & Savvides, A. & Buonomano, A., 2022. "Building integration of active solar energy systems for façades renovation in the urban fabric: Effects on the thermal comfort in outdoor public spaces in Naples and Thessaloniki," Renewable Energy, Elsevier, vol. 190(C), pages 30-47.
    10. Ahmad Adeel & Bruno Notteboom & Ansar Yasar & Kris Scheerlinck & Jeroen Stevens, 2021. "Sustainable Streetscape and Built Environment Designs around BRT Stations: A Stated Choice Experiment Using 3D Visualizations," Sustainability, MDPI, vol. 13(12), pages 1-21, June.
    11. Arnaud Z. Dragicevic, 2019. "Market Coordination Under Non-Equilibrium Dynamics," Networks and Spatial Economics, Springer, vol. 19(3), pages 697-715, September.
    12. Taner Akan & Tim Solle, 2022. "Do macroeconomic and financial governance matter? Evidence from Germany, 1950–2019," Journal of Economic Interaction and Coordination, Springer;Society for Economic Science with Heterogeneous Interacting Agents, vol. 17(4), pages 993-1045, October.
    13. Samih Azar & Ali Bolbol & Alexandre Mouradian, 2016. "Profitability of Banks in Lebanon: Some Theoretical and Empirical Results," International Journal of Economics and Finance, Canadian Center of Science and Education, vol. 8(7), pages 233-233, July.
    14. Ferlito, Carmelo, 2015. "Ludwig M. Lachmann contro la Scuola di Cambridge [Ludwig M. Lachmann against the Cambridge School]," MPRA Paper 67759, University Library of Munich, Germany.
    15. Octavian-Dragomir JORA & Alexandru BUTISEACÃ & Mihaela IACOB, 2017. "Seeking Truth from Facts and Figures Only? The Logic of Economics and China’s Miracles," REVISTA DE MANAGEMENT COMPARAT INTERNATIONAL/REVIEW OF INTERNATIONAL COMPARATIVE MANAGEMENT, Faculty of Management, Academy of Economic Studies, Bucharest, Romania, vol. 18(5), pages 545-562, December.
    16. Kienast, Felix & Frick, Jacqueline & van Strien, Maarten J. & Hunziker, Marcel, 2015. "The Swiss Landscape Monitoring Program – A comprehensive indicator set to measure landscape change," Ecological Modelling, Elsevier, vol. 295(C), pages 136-150.
    17. Grilli, Gianluca & Fratini, Roberto & Marone, Enrico & Sacchelli, Sandro, 2020. "A spatial-based tool for the analysis of payments for forest ecosystem services related to hydrogeological protection," Forest Policy and Economics, Elsevier, vol. 111(C).
    18. Fernández-Villaverde, Jesús, 2016. "Magna Carta, the rule of law, and the limits on government," International Review of Law and Economics, Elsevier, vol. 47(S), pages 22-28.
    19. Pierre-Guillaume Méon & Khalid Sekkat, 2016. "A time to throw stones, a time to reap: How long does it take for democratic transitions to improve institutional outcomes?," Working Papers CEB 16-016, ULB -- Universite Libre de Bruxelles.
    20. Martin Mabunda Baluku & Julius Fred Kikooma & Edward Bantu & Kathleen Otto, 2018. "Psychological capital and entrepreneurial outcomes: the moderating role of social competences of owners of micro-enterprises in East Africa," Journal of Global Entrepreneurship Research, Springer;UNESCO Chair in Entrepreneurship, vol. 8(1), pages 1-23, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2022:i:1:p:328-:d:1014766. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.