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Uncertainty tolerance among experts involved in drug reimbursement recommendations: Qualitative evidence from HTA committees in Canada and Poland

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  • Wranik, Wiesława Dominika
  • Gambold, Liesl
  • Peacock, Stuart

Abstract

Drug reimbursement decisions often rely on health technology assessment (HTA). Increasingly, new drugs have limited clinical evidence and uncertain clinical benefit. Our goal was to describe how members of drug advisory committees and other stakeholders conceptualize and tolerate uncertainty and how they rationalize uncertainty tolerance.

Suggested Citation

  • Wranik, Wiesława Dominika & Gambold, Liesl & Peacock, Stuart, 2021. "Uncertainty tolerance among experts involved in drug reimbursement recommendations: Qualitative evidence from HTA committees in Canada and Poland," Health Policy, Elsevier, vol. 125(3), pages 307-319.
    • Handle: RePEc:eee:hepoli:v:125:y:2021:i:3:p:307-319
    DOI: 10.1016/j.healthpol.2020.12.007
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    References listed on IDEAS

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    1. Cerri, Karin H & Knapp, Martin & Fernandez, Jose-Luis, 2014. "Decision making by NICE: examining the influences of evidence, process and context – CORRIGENDUM," Health Economics, Policy and Law, Cambridge University Press, vol. 9(4), pages 435-435, October.
    2. Kaye Knight & Amanda Kenny & Ruth Endacott, 2016. "From expert generalists to ambiguity masters: using ambiguity tolerance theory to redefine the practice of rural nurses," Journal of Clinical Nursing, John Wiley & Sons, vol. 25(11-12), pages 1757-1765, June.
    3. Chris Skedgel & Dominika Wranik & Min Hu, 2018. "The Relative Importance of Clinical, Economic, Patient Values and Feasibility Criteria in Cancer Drug Reimbursement in Canada: A Revealed Preferences Analysis of Recommendations of the Pan-Canadian On," PharmacoEconomics, Springer, vol. 36(4), pages 467-475, April.
    4. Cerri, Karin H. & Knapp, Martin & Fernandez, Jose-Luis, 2014. "Decision making by NICE: examining the influences of evidence, process and context," Health Economics, Policy and Law, Cambridge University Press, vol. 9(2), pages 119-141, April.
    5. Warren Linley & Dyfrig Hughes, 2012. "Reimbursement Decisions of the All Wales Medicines Strategy Group," PharmacoEconomics, Springer, vol. 30(9), pages 779-794, September.
    6. Ferrario, Alessandra & Kanavos, Panos, 2015. "Dealing with uncertainty and high prices of new medicines: A comparative analysis of the use of managed entry agreements in Belgium, England, the Netherlands and Sweden," Social Science & Medicine, Elsevier, vol. 124(C), pages 39-47.
    7. Janneke Grutters & Marjolein Asselt & Kalipso Chalkidou & Manuela Joore, 2015. "The Authors’ Reply: Comment on “Healthy Decisions: Towards Uncertainty Tolerance in Healthcare Policy”," PharmacoEconomics, Springer, vol. 33(9), pages 983-983, September.
    8. repec:bla:glopol:v:8:y:2017:i::p:84-92 is not listed on IDEAS
    9. W. Dominika Wranik & Liesl Gambold & Natasha Hanson & Adrian Levy, 2017. "The evolution of the cancer formulary review in Canada: Can centralization improve the use of economic evaluation?," International Journal of Health Planning and Management, Wiley Blackwell, vol. 32(2), pages 232-260, April.
    10. Kawalec, Paweł & Sagan, Anna & Stawowczyk, Ewa & Kowalska-Bobko, Iwona & Mokrzycka, Anna, 2016. "Implementation of the 2011 Reimbursement Act in Poland: Desired and undesired effects of the changes in reimbursement policy," Health Policy, Elsevier, vol. 120(4), pages 356-361.
    11. Panos Kanavos & Olivier Wouters & Panos Kanavos & Alessandra Ferrario & Giovanni Tafuri & Paolo Siviero, 2017. "Managing Risk and Uncertainty in Health Technology Introduction: The Role of Managed Entry Agreements," Global Policy, London School of Economics and Political Science, vol. 8(s2), pages 84-92, March.
    12. Hillen, Marij A. & Gutheil, Caitlin M. & Strout, Tania D. & Smets, Ellen M.A. & Han, Paul K.J., 2017. "Tolerance of uncertainty: Conceptual analysis, integrative model, and implications for healthcare," Social Science & Medicine, Elsevier, vol. 180(C), pages 62-75.
    13. Mikael Svensson & Fredrik Nilsson & Karl Arnberg, 2015. "Reimbursement Decisions for Pharmaceuticals in Sweden: The Impact of Disease Severity and Cost Effectiveness," PharmacoEconomics, Springer, vol. 33(11), pages 1229-1236, November.
    14. Angela Rocchi & Elizabeth Miller & Robert Hopkins & Ron Goeree, 2012. "Common Drug Review Recommendations," PharmacoEconomics, Springer, vol. 30(3), pages 229-246, March.
    15. Janneke Grutters & Marjolein Asselt & Kalipso Chalkidou & Manuela Joore, 2015. "Healthy Decisions: Towards Uncertainty Tolerance in Healthcare Policy," PharmacoEconomics, Springer, vol. 33(1), pages 1-4, January.
    16. Warren Linley & Dyfrig Hughes, 2013. "Decision-Makers’ Preferences for Approving New Medicines in Wales: A Discrete-Choice Experiment with Assessment of External Validity," PharmacoEconomics, Springer, vol. 31(4), pages 345-355, April.
    17. Malinowski, Krzysztof Piotr & Kawalec, Paweł & Trąbka, Wojciech, 2016. "Impact of patient outcomes and cost aspects on reimbursement recommendations in Poland in 2012–2014," Health Policy, Elsevier, vol. 120(11), pages 1249-1255.
    18. Karl E. Weick & Kathleen M. Sutcliffe & David Obstfeld, 2005. "Organizing and the Process of Sensemaking," Organization Science, INFORMS, vol. 16(4), pages 409-421, August.
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