IDEAS home Printed from https://ideas.repec.org/p/wop/safiwp/97-07-065.html
   My bibliography  Save this paper

Selection Dynamics in Autocatalytic Systems: Templates Replicating Through Binary Ligation

Author

Listed:

Abstract

The theory of autocatalytic binary ligation is reviewed within the context of a rigorously applied Michaelis-Menten quasi-steady-state approximation to obtain explicit analytical results describing time-course data from experiments. A detailed protocol for the step-wise elucidation of a minimal set of experimental parameters is outlined. The kinetic equations are then generalized to case of self- and cross-catalysis among an arbitrary number of different templates and applied to experiments involving just two templates. It is observed that in systems incorporating multiple templates coexistence of all species is the norm because their synthesis follows a parabolic growth law. Only under certain stringent conditions is exponential growth, and hence, Darwinian competition, observed. Our results are applicable to classical case of self-replicating nucleic acids and their analogues as well as to newly discovered self-replicating peptides.

Suggested Citation

  • Peter R. Wills & Stuart A. Kauffman & Barbel M. R. Stadler & Peter F. Stadler, 1997. "Selection Dynamics in Autocatalytic Systems: Templates Replicating Through Binary Ligation," Working Papers 97-07-065, Santa Fe Institute.
    • Handle: RePEc:wop:safiwp:97-07-065
    as

    Download full text from publisher

    To our knowledge, this item is not available for download. To find whether it is available, there are three options:
    1. Check below whether another version of this item is available online.
    2. Check on the provider's web page whether it is in fact available.
    3. Perform a search for a similarly titled item that would be available.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:wop:safiwp:97-07-065. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thomas Krichel (email available below). General contact details of provider: https://edirc.repec.org/data/epstfus.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.