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Measurement of Cumulative Physiological Dysregulation in an Older Population

Author

Listed:
  • Christopher L. Seplaki

    (Princeton University)

  • Noreen Goldman

    (Princeton University)

  • Maxine Weinstein

    (Georgetown University)

  • Yu-Hsuan Lin

    (Bureau of Health Promotion, Center for Population and Survey Research, Department of Health, Taichung, Taiwan)

Abstract

Theories of allostatic load postulate that an important pathway connecting the social environment with health involves biological responses to stressful stimuli and subsequent dysregulation of interrelated physiological systems. We formulate a new measure for cumulative physiological dysregulation using a grade of membership model estimated with biodemographic data from a national sample of older Taiwanese. We investigate associations between the measure and physical, psychological, and cognitive function. The results provide insights into the relationships between a set of biological profiles and various health outcomes, identify limitations of earlier approaches, and underscore next steps in the development of improved formulations of physiological dysregulation.

Suggested Citation

  • Christopher L. Seplaki & Noreen Goldman & Maxine Weinstein & Yu-Hsuan Lin, 2004. "Measurement of Cumulative Physiological Dysregulation in an Older Population," Working Papers 295, Princeton University, Woodrow Wilson School of Public and International Affairs, Office of Population Research..
    • Handle: RePEc:pri:opopre:opr0402.pdf
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    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General

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