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Methodological and ethical concerns in a study on effect of COVID-19 vaccine among health care workers in a medical college of India

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  • Srijit Mishra

    (Indira Gandhi Institute of Development Research)

Abstract

A critical look into the nature of observational data from a study on effect of COVID-19 vaccine of health care workers points out some methodological and ethical concerns. Further analysis with relative and absolute risk reductions indicate that the effect size was lower, at times not significant and even negative when one tried to compare fully vaccinated with single dose, or tried to use person days (rather than number of health care workers) to account for differences in exposure. This, on the one hand, calls for caution in the media while reporting such results, and on the other hand, it calls for transparency and sharing of information in the public domain to facilitate wider scrutiny and informed debate.

Suggested Citation

  • Srijit Mishra, 2021. "Methodological and ethical concerns in a study on effect of COVID-19 vaccine among health care workers in a medical college of India," Indira Gandhi Institute of Development Research, Mumbai Working Papers 2021-023, Indira Gandhi Institute of Development Research, Mumbai, India.
    • Handle: RePEc:ind:igiwpp:2021-023
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    File URL: http://www.igidr.ac.in/pdf/publication/WP-2021-023.pdf
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    References listed on IDEAS

    as
    1. Andreas Radbruch & Hyun-Dong Chang, 2021. "A long-term perspective on immunity to COVID," Nature, Nature, vol. 595(7867), pages 359-360, July.
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    Cited by:

    1. Srijit Mishra, "undated". "Herd immunity, COVID-19 and vaccination: Ssome propositions," Indira Gandhi Institute of Development Research, Mumbai Working Papers 2021-024, Indira Gandhi Institute of Development Research, Mumbai, India.

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    More about this item

    Keywords

    Absolute risk reduction; COVID-19; health care workers; relative risk reduction;
    All these keywords.

    JEL classification:

    • C19 - Mathematical and Quantitative Methods - - Econometric and Statistical Methods and Methodology: General - - - Other
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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