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A “Good” Smoke? The Off-Label Use of Cannabidiol to Reduce Cannabis Use

Author

Listed:
  • Davide Fortin

    (UP1 - Université Paris 1 Panthéon-Sorbonne)

  • Vincent Di Beo

    (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale - IRD - Institut de Recherche pour le Développement - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale, ISSPAM - Institut des sciences de la santé publique [Marseille])

  • Sophie Massin

    (LEM - Lille économie management - UMR 9221 - UA - Université d'Artois - UCL - Université catholique de Lille - Université de Lille - CNRS - Centre National de la Recherche Scientifique)

  • Yann Bisiou

    (CORHIS - Communication, Ressources Humaines et Intervention Sociale - UPVM - Université Paul-Valéry - Montpellier 3 - UPVD - Université de Perpignan Via Domitia)

  • Patrizia Carrieri

    (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale - IRD - Institut de Recherche pour le Développement - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale, ISSPAM - Institut des sciences de la santé publique [Marseille])

  • Tangui Barré

    (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale - IRD - Institut de Recherche pour le Développement - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale, ISSPAM - Institut des sciences de la santé publique [Marseille])

Abstract

Although cannabis use is common in France, it is still criminalized. Cannabidiol (CBD) products, including CBD-rich cannabis, are legally available. Although previous results suggested that CBD may have benefits for people with cannabis use disorder, there is a lack of data on cannabis users who use CBD to reduce their cannabis consumption. We aimed to identify (i) correlates of this motive, and (ii) factors associated with successful attempts to reduce cannabis use. Methods A cross-sectional online survey among French-speaking CBD and cannabis users was conducted. Logistic regressions were performed to identify correlates of using CBD to reduce cannabis consumption and correlates of reporting a large reduction. Results Eleven percent ( n = 105) of our study sample reported they primarily used CBD to reduce cannabis consumption. Associated factors included smoking tobacco cigarettes (adjusted odds ratio (aOR) [95% confidence interval (CI)] 2.17 [1.3–3.62], p = 0.003) and drinking alcohol (aOR [95%CI] 1.8 [1.02–3.18], p = 0.042). Of these 105, 83% used CBD-rich cannabis to smoke, and 58.7% reported a large reduction in cannabis consumption. This large reduction was associated with non-daily cannabis use (aOR [95%CI] 7.14 [2.4–20.0], p < 0.001) and daily CBD use (aOR [95%CI] 5.87 [2.09–16.47], p = 0.001). A reduction in cannabis withdrawal symptoms thanks to CBD use was the most-cited effect at play in self-observed cannabis reduction. Conclusions Cannabis use reduction is a reported motive for CBD use—especially CBD-rich cannabis to smoke—in France. More studies are needed to explore practices associated with this motive and to accurately assess CBD effectiveness.

Suggested Citation

  • Davide Fortin & Vincent Di Beo & Sophie Massin & Yann Bisiou & Patrizia Carrieri & Tangui Barré, 2022. "A “Good” Smoke? The Off-Label Use of Cannabidiol to Reduce Cannabis Use," Post-Print hal-03702711, HAL.
    • Handle: RePEc:hal:journl:hal-03702711
    DOI: 10.3389/fpsyt.2022.829944
    Note: View the original document on HAL open archive server: https://hal.science/hal-03702711
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    References listed on IDEAS

    as
    1. Guillaume Airagnes & Cédric Lemogne & Pierre Meneton & Marie Plessz & Marcel Goldberg & Nicolas Hoertel & Yves Roquelaure & Frédéric Limosin & Marie Zins, 2019. "Alcohol, tobacco and cannabis use are associated with job loss at follow-up: Findings from the CONSTANCES cohort," PLOS ONE, Public Library of Science, vol. 14(9), pages 1-16, September.
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    Cited by:

    1. Davide Fortin, 2023. "Light cannabis as a substitute for addictive substances: A cross-sectional analysis of survey data in France and Italy," French Stata Users' Group Meetings 2023 10, Stata Users Group.

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      Keywords

      cannabidiol (CBD); cannabis (marijuana); cannabis use disorder (CUD); smoking; France; harm reduction;
      All these keywords.

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