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Application of Ex-Vivo/3D Organoid Models in COVID-19 Research

In: Biotechnology to Combat COVID-19

Author

Listed:
  • Allen Thayakumar Basanthakumar

Abstract

COVID-19 treatment methods based on 3D organoids and ex-vivo platforms are analyzed in this chapter. Initially, the platforms available for cell culture and its working characteristics are explained. Subsequently discusses the organoids with their definition and included their uses in various applications. Further, the chapter extends to describe the uses of different organoids with their use in different stages. Most of these methods utilized the 3D ex-vivo cell culture method to develop organoids and test them over infected tissues. Based on the study in this chapter, it is found that the demonstration of active replication of the human organoids culture system of lungs is found to be more helpful for COVID-19 treatment.

Suggested Citation

  • Allen Thayakumar Basanthakumar, 2022. "Application of Ex-Vivo/3D Organoid Models in COVID-19 Research," Chapters, in: Megha Agrawal & Shyamasri Biswas (ed.), Biotechnology to Combat COVID-19, IntechOpen.
  • Handle: RePEc:ito:pchaps:225359
    DOI: 10.5772/intechopen.99100
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    File URL: https://www.intechopen.com/chapters/77695
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    More about this item

    Keywords

    COVID-19; 3D exvivo; 3D Organoid models; invivo; cell culture;
    All these keywords.

    JEL classification:

    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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