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CEMIMIX: Stata module to perform reference-based multiple imputation of cost-effectiveness data in clinical trials

Author

Listed:
  • Baptiste Leurent

    (UCL Department of Statistical Science)

  • Suzie Cro

    (Imperial College London, UK)

Programming Language

Stata

Abstract

The cemimix module imputes missing numerical cost and/or effectiveness variables following a reference-based multiple imputation approach. It follows the method described in Leurent et al. (Pharmacoeconomics 2020), based on the work by Carpenter, Roger, and Kenward (Journal of Biopharmaceutical Statistics, 2013). It allows for various missing data assumptions, including 'Missing at random' (MAR), 'Jump to reference' (J2R), 'Copy increments in reference' (CIR), 'Last mean carried forward (LMCF), and 'Baseline mean carried forward' (BMCF). It was primarily developed for the imputation of cost-effectiveness data in randomised controlled trials but can be used more generally for the imputation of up to two continuous outcomes, measured at a single follow-up point or longitudinally (repeated measures).

Suggested Citation

  • Baptiste Leurent & Suzie Cro, 2022. "CEMIMIX: Stata module to perform reference-based multiple imputation of cost-effectiveness data in clinical trials," Statistical Software Components S459096, Boston College Department of Economics.
    • Handle: RePEc:boc:bocode:s459096
    Note: This module should be installed from within Stata by typing "ssc install cemimix". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
    as

    Download full text from publisher

    File URL: http://fmwww.bc.edu/repec/bocode/c/cemimix.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/c/cemimix.sthlp
    File Function: help file
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/_/10TT.dta
    File Function: sample data file
    Download Restriction: no
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