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Bayesian prediction for two-stage sequential analysis in clinical trials

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  • Hayet Merabet
  • Ahlam Labdaoui
  • Pierre Druilhet

Abstract

This article deals with a Bayesian predictive approach for two-stage sequential analyses in clinical trials, applied to both frequentist and Bayesian tests. We propose to make a predictive inference based on the notion of satisfaction index and the data accrued so far together with future data. The computations and the simulation results concern an inferential problem, related to the binomial model.

Suggested Citation

  • Hayet Merabet & Ahlam Labdaoui & Pierre Druilhet, 2017. "Bayesian prediction for two-stage sequential analysis in clinical trials," Communications in Statistics - Theory and Methods, Taylor & Francis Journals, vol. 46(19), pages 9807-9816, October.
    • Handle: RePEc:taf:lstaxx:v:46:y:2017:i:19:p:9807-9816
    DOI: 10.1080/03610926.2016.1222438
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