IDEAS home Printed from https://ideas.repec.org/a/taf/gcmbxx/v26y2023i7p807-819.html
   My bibliography  Save this article

Internal flow field analysis of heterogeneous porous scaffold for bone tissue engineering

Author

Listed:
  • Xiaokang Wang
  • Jigang Chen
  • Yabin Guan
  • Li Sun
  • Yongxing Kang

Abstract

The internal pore structure of the porous scaffold for bone tissue engineering and the pressure and velocity distributions of its flow field affect the attachment, proliferation and differentiation of osteoblasts. The permeability of the porous scaffold determines its ability to transport cellular nutrients and metabolites. Therefore, studying the fluid flow characteristics of the porous scaffold plays a vital role in its biological applications. Heterogeneous porous scaffolds (HPS) with irregular internal pore structure have more bionic characteristics of natural structure than uniform porous scaffolds with regular internal pore structure. In order to comprehensively grasp the biological properties of HPS, this article designed HPS with different porosities based on the Voronoi generation method and random theory, and then used computational fluid dynamics (CFD)software to conduct fluid flow simulations. The velocity and pressure distribution rules of the internal flow field of HPS with different porosities were obtained by CFD simulation analysis, and the relationship between the porosity and the distribution rules was studied. Furthermore, the permeabilities of HPS with different porosities were calculated based on Darcy's law, and the influence rule of porosity on the permeability was obtained.

Suggested Citation

  • Xiaokang Wang & Jigang Chen & Yabin Guan & Li Sun & Yongxing Kang, 2023. "Internal flow field analysis of heterogeneous porous scaffold for bone tissue engineering," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 26(7), pages 807-819, May.
  • Handle: RePEc:taf:gcmbxx:v:26:y:2023:i:7:p:807-819
    DOI: 10.1080/10255842.2022.2089025
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1080/10255842.2022.2089025
    Download Restriction: Access to full text is restricted to subscribers.

    File URL: https://libkey.io/10.1080/10255842.2022.2089025?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:taf:gcmbxx:v:26:y:2023:i:7:p:807-819. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Longhurst (email available below). General contact details of provider: http://www.tandfonline.com/gcmb .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.