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Investigating Potential Gender-Based Differential Item Functioning for Items in the Kansas City Cardiomyopathy Questionnaire (KCCQ) Physical Limitations Domain

Author

Listed:
  • Theresa M. Coles

    (Duke University School of Medicine)

  • Li Lin

    (Duke University School of Medicine)

  • Kevin Weinfurt

    (Duke University School of Medicine)

  • Bryce B. Reeve

    (Duke University School of Medicine)

  • John A. Spertus

    (University of Missouri-Kansas City
    University of Missouri-Kansas City)

  • Robert J. Mentz

    (Duke University Medical Center)

  • Ileana L. Piña

    (Wayne State University, Central Michigan University
    U.S. Food and Drug Administration)

  • Fraser D. Bocell

    (U.S. Food and Drug Administration)

  • Michelle E. Tarver

    (U.S. Food and Drug Administration)

  • Anindita Saha

    (U.S. Food and Drug Administration)

  • Brittany Caldwell

    (U.S. Food and Drug Administration)

Abstract

Women with heart failure report worse health-related quality of life on average, than men. This may result from actual differences in care or differing interpretations of and responses to survey questions. We investigated potential gender-based differential item functioning on the Kansas City Cardiomyopathy Questionnaire (KCCQ) Physical Limitations domain. Using data from the HF-ACTION trial, a multicenter, randomized controlled trial of exercise training in patients with chronic heart failure with reduced ejection fraction (661 women, 1670 men), we assessed gender-based differential item functioning using a Wald test based on item response theory and ordinal logistic regression. Both methods evaluated how men and women responded to each KCCQ item after adjusting for physical limitation status. No item exhibited statistically significant differential item functioning using the Wald method. Two items exhibited differential item functioning using the ordinal logistic regression method (KCCQ1e: Climbing a flight of stairs without stopping; KCCQ1f: Hurrying or jogging) (P

Suggested Citation

  • Theresa M. Coles & Li Lin & Kevin Weinfurt & Bryce B. Reeve & John A. Spertus & Robert J. Mentz & Ileana L. Piña & Fraser D. Bocell & Michelle E. Tarver & Anindita Saha & Brittany Caldwell, 2023. "Investigating Potential Gender-Based Differential Item Functioning for Items in the Kansas City Cardiomyopathy Questionnaire (KCCQ) Physical Limitations Domain," Applied Research in Quality of Life, Springer;International Society for Quality-of-Life Studies, vol. 18(4), pages 1785-1798, August.
    • Handle: RePEc:spr:ariqol:v:18:y:2023:i:4:d:10.1007_s11482-023-10162-3
    DOI: 10.1007/s11482-023-10162-3
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