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The Association Between Vitamin D Level and Chest Pain, Anxiety, and Fatigue in Patients With Coronary Artery Disease

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  • Wejdan A. Khater
  • Mohammad Ali Alfarkh
  • Aladeen Allnoubani

Abstract

This study sought to assess the association between vitamin D deficiency (VDD) and chest pain, anxiety, and fatigue in patients with coronary artery disease (CAD). A cross-sectional study was conducted to collect data from a sample of 90 participants with CAD. Serum 25OHD3 was measured using a radioimmunoassay procedure. Chest pain was assessed using the Numeric Pain Rating Scale, anxiety using the Anxiety Subscale, and fatigue by the General Fatigue subscale. The majority of participants (80%) had VDD. Results showed that the level of vitamin D was significantly negatively associated with chest pain ( r  = −.43, p  = .00); anxiety ( r  = −.466, p  = .00); and fatigue ( r  = −.25, p  = .018). Findings suggest the role of VDD in heightened central sensitivity in cardiac-related symptoms such as chest pain, anxiety, and fatigue. Patients with CAD should be monitored for VDD so that the condition can be corrected.

Suggested Citation

  • Wejdan A. Khater & Mohammad Ali Alfarkh & Aladeen Allnoubani, 2023. "The Association Between Vitamin D Level and Chest Pain, Anxiety, and Fatigue in Patients With Coronary Artery Disease," Clinical Nursing Research, , vol. 32(3), pages 639-647, March.
    • Handle: RePEc:sae:clnure:v:32:y:2023:i:3:p:639-647
    DOI: 10.1177/10547738221126325
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    1. Jeffrey W. Young & Sheila Melander, 2013. "Evaluating Symptoms to Improve Quality of Life in Patients with Chronic Stable Angina," Nursing Research and Practice, Hindawi, vol. 2013, pages 1-8, December.
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