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Increasing adverse drug reaction reporting—How can we do better?

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  • Miri Potlog Shchory
  • Lee H Goldstein
  • Lidia Arcavi
  • Renata Shihmanter
  • Matitiahu Berkovitch
  • Amalia Levy

Abstract

Adverse drug reactions (ADRs) are associated with morbidity and mortality worldwide. Although national systems for reporting ADRs exist there is a low reporting rate. The aim of the current study was to evaluate an intervention plan for improving ADRs reporting among medical professionals (physicians and nurses). A multicentre intervention study was conducted, in which one medical centre was randomly assigned to the intervention group and two medical centres to the control group. The study consisted of 3 phases: baseline data collection, intervention and follow-up of the reporting rate. The questionnaire that was filled in at base line and at the end of study, contained questions about personal/professional demographic variables, and statements regarding knowledge of and behaviour toward ADRs reporting. The intervention program consisted of posters, lectures, distant electronic learning and reminders. An increase in the number of ADRs reports was noted in the intervention group (74 times higher than in the control group) during the intervention period, which was gradually decreased with as the study progressed (adjusted O.R = 74.1, 95% CI = 21.11–260.1, p

Suggested Citation

  • Miri Potlog Shchory & Lee H Goldstein & Lidia Arcavi & Renata Shihmanter & Matitiahu Berkovitch & Amalia Levy, 2020. "Increasing adverse drug reaction reporting—How can we do better?," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-15, August.
  • Handle: RePEc:plo:pone00:0235591
    DOI: 10.1371/journal.pone.0235591
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