IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0213974.html
   My bibliography  Save this article

Differentiating weight-restored anorexia nervosa and body dysmorphic disorder using neuroimaging and psychometric markers

Author

Listed:
  • Don A Vaughn
  • Wesley T Kerr
  • Teena D Moody
  • Gigi K Cheng
  • Francesca Morfini
  • Aifeng Zhang
  • Alex D Leow
  • Michael A Strober
  • Mark S Cohen
  • Jamie D Feusner

Abstract

Anorexia nervosa (AN) and body dysmorphic disorder (BDD) are potentially life-threatening conditions whose partially overlapping phenomenology—distorted perception of appearance, obsessions/compulsions, and limited insight—can make diagnostic distinction difficult in some cases. Accurate diagnosis is crucial, as the effective treatments for AN and BDD differ. To improve diagnostic accuracy and clarify the contributions of each of the multiple underlying factors, we developed a two-stage machine learning model that uses multimodal, neurobiology-based, and symptom-based quantitative data as features: task-based functional magnetic resonance imaging data using body visual stimuli, graph theory metrics of white matter connectivity from diffusor tensor imaging, and anxiety, depression, and insight psychometric scores. In a sample of unmedicated adults with BDD (n = 29), unmedicated adults with weight-restored AN (n = 24), and healthy controls (n = 31), the resulting model labeled individuals with an accuracy of 76%, significantly better than the chance accuracy of 35% (p^

Suggested Citation

  • Don A Vaughn & Wesley T Kerr & Teena D Moody & Gigi K Cheng & Francesca Morfini & Aifeng Zhang & Alex D Leow & Michael A Strober & Mark S Cohen & Jamie D Feusner, 2019. "Differentiating weight-restored anorexia nervosa and body dysmorphic disorder using neuroimaging and psychometric markers," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-16, May.
    • Handle: RePEc:plo:pone00:0213974
    DOI: 10.1371/journal.pone.0213974
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213974
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0213974&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0213974?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Kate Tchanturia & Helen Davies & Marion Roberts & Amy Harrison & Michiko Nakazato & Ulrike Schmidt & Janet Treasure & Robin Morris, 2012. "Poor Cognitive Flexibility in Eating Disorders: Examining the Evidence using the Wisconsin Card Sorting Task," PLOS ONE, Public Library of Science, vol. 7(1), pages 1-5, January.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mudan Wu & Mechthild Hartmann & Mandy Skunde & Wolfgang Herzog & Hans-Christoph Friederich, 2013. "Inhibitory Control in Bulimic-Type Eating Disorders: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-13, December.
    2. Emma Boswell Dean & Frank Schilbach & Heather Schofield, 2017. "Poverty and Cognitive Function," NBER Chapters, in: The Economics of Poverty Traps, pages 57-118, National Bureau of Economic Research, Inc.
    3. Emanuele Maria Giusti & Chiara Manna & Anna Scolari & José M. Mestre & Tamara Prevendar & Gianluca Castelnuovo & Giada Pietrabissa, 2021. "The Relationship between Emotional Intelligence, Obesity and Eating Disorder in Children and Adolescents: A Systematic Mapping Review," IJERPH, MDPI, vol. 18(4), pages 1-13, February.
    4. Christina Wierenga & Amanda Bischoff-Grethe & A James Melrose & Emily Grenesko-Stevens & Zoë Irvine & Angela Wagner & Alan Simmons & Scott Matthews & Wai-Ying Wendy Yau & Christine Fennema-Notestine &, 2014. "Altered BOLD Response during Inhibitory and Error Processing in Adolescents with Anorexia Nervosa," PLOS ONE, Public Library of Science, vol. 9(3), pages 1-13, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0213974. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.