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Changes in choroidal area following trabeculectomy: Long-term effect of intraocular pressure reduction

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  • Hirokazu Kojima
  • Kazuyuki Hirooka
  • Shozo Sonoda
  • Taiji Sakamoto
  • Yoshiaki Kiuchi

Abstract

Purpose: To evaluate changes in the macula and peripapillary choroidal area at one year after trabeculectomy in order to determine the effect of intraocular pressure (IOP) changes. Methods: This prospective longitudinal study examined 30 eyes of 30 patients with glaucoma that was uncontrolled by medical therapy. At 1 day before and at 1 year after the trabeculectomy surgery, macular and peripapillary choroidal images were recorded by enhanced depth imaging optical coherence tomography (EDI-OCT). Luminal and interstitial areas were converted to binary images using the Niblack method. Factors influencing the macular choroidal and peripapillary area were examined by multivariate analysis. Results: After trabeculectomy, the mean IOP was 10.8±3.2 mmHg compared to 17.8±7.2 mmHg at baseline (P

Suggested Citation

  • Hirokazu Kojima & Kazuyuki Hirooka & Shozo Sonoda & Taiji Sakamoto & Yoshiaki Kiuchi, 2019. "Changes in choroidal area following trabeculectomy: Long-term effect of intraocular pressure reduction," PLOS ONE, Public Library of Science, vol. 14(3), pages 1-11, March.
    • Handle: RePEc:plo:pone00:0209145
    DOI: 10.1371/journal.pone.0209145
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    References listed on IDEAS

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    1. Yong Ju Song & Young Kook Kim & Jin Wook Jeoung & Ki Ho Park, 2016. "Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-12, June.
    2. Hirokazu Kojima & Kazuyuki Hirooka & Eri Nitta & Kaori Ukegawa & Shozo Sonoda & Taiji Sakamoto, 2018. "Changes in choroidal area after intraocular pressure reduction following trabeculectomy," PLOS ONE, Public Library of Science, vol. 13(8), pages 1-11, August.
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    1. Hirokazu Kojima & Kazuyuki Hirooka & Eri Nitta & Shozo Sonoda & Taiji Sakamoto & Yoshiaki Kiuchi, 2020. "Assessment of primary open-angle glaucoma peripapillary and macular choroidal area using enhanced depth imaging optical coherence tomography," PLOS ONE, Public Library of Science, vol. 15(4), pages 1-10, April.

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    1. Hirokazu Kojima & Kazuyuki Hirooka & Eri Nitta & Shozo Sonoda & Taiji Sakamoto & Yoshiaki Kiuchi, 2020. "Assessment of primary open-angle glaucoma peripapillary and macular choroidal area using enhanced depth imaging optical coherence tomography," PLOS ONE, Public Library of Science, vol. 15(4), pages 1-10, April.

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