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Characterization of the CPAP-treated patient population in Catalonia

Author

Listed:
  • Cecilia Turino
  • Sandra Bertran
  • Ricard Gavaldá
  • Ivan Teixidó
  • Holger Woehrle
  • Montserrat Rué
  • Francesc Solsona
  • Joan Escarrabill
  • Cristina Colls
  • Anna García-Altés
  • Jordi de Batlle
  • Manuel Sánchez de-la-Torre
  • Ferran Barbé

Abstract

There are different phenotypes of obstructive sleep apnoea (OSA), many of which have not been characterised. Identification of these different phenotypes is important in defining prognosis and guiding the therapeutic strategy. The aim of this study was to characterise the entire population of continuous positive airway pressure (CPAP)-treated patients in Catalonia and identify specific patient profiles using cluster analysis.A total of 72,217 CPAP-treated patients who contacted the Catalan Health System (CatSalut) during the years 2012 and 2013 were included. Six clusters were identified, classified as “Neoplastic patients” (Cluster 1, 10.4%), “Metabolic syndrome patients” (Cluster 2, 27.7%), “Asthmatic patients” (Cluster 3, 5.8%), “Musculoskeletal and joint disorder patients” (Cluster 4, 10.3%), “Patients with few comorbidities” (Cluster 5, 35.6%) and “Oldest and cardiac disease patients” (Cluster 6, 10.2%). Healthcare facility use and mortality were highest in patients from Cluster 1 and 6. Conversely, patients in Clusters 2 and 4 had low morbidity, mortality and healthcare resource use.Our findings highlight the heterogeneity of CPAP-treated patients, and suggest that OSA is associated with a different prognosis in the clusters identified. These results suggest the need for a comprehensive and individualised approach to CPAP treatment of OSA.

Suggested Citation

  • Cecilia Turino & Sandra Bertran & Ricard Gavaldá & Ivan Teixidó & Holger Woehrle & Montserrat Rué & Francesc Solsona & Joan Escarrabill & Cristina Colls & Anna García-Altés & Jordi de Batlle & Manuel , 2017. "Characterization of the CPAP-treated patient population in Catalonia," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-12, September.
    • Handle: RePEc:plo:pone00:0185191
    DOI: 10.1371/journal.pone.0185191
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    References listed on IDEAS

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    1. Sébastien Bailly & Marie Destors & Yves Grillet & Philippe Richard & Bruno Stach & Isabelle Vivodtzev & Jean-Francois Timsit & Patrick Lévy & Renaud Tamisier & Jean-Louis Pépin & scientific council an, 2016. "Obstructive Sleep Apnea: A Cluster Analysis at Time of Diagnosis," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-12, June.
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