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Clinical utility of the modified Glasgow prognostic score in lung cancer: A meta-analysis

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  • Jing Jin
  • Kejia Hu
  • Yongzhao Zhou
  • Weimin Li

Abstract

Objective: To perform a meta-analysis of prospective and retrospective studies exploring the association of the modified Glasgow prognostic score (mGPS) with overall survival (OS) in patients with lung cancer. Methods: Relevant studies were identified by searching the Cochrane Library, Web of Science, Embase and PubMed until April 16, 2017. We combined hazard ratios (HRs) and 95% confidence intervals (CIs) to assess the correlation between mGPS and OS in patients with lung cancer. Results: Eleven studies involving 5817 participants from several countries were included in the meta-analysis. In a pooled analysis of all studies, elevated mGPS predicted poorer OS (HR = 1.77; 95% CI: 1.35–2.31; P

Suggested Citation

  • Jing Jin & Kejia Hu & Yongzhao Zhou & Weimin Li, 2017. "Clinical utility of the modified Glasgow prognostic score in lung cancer: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-13, September.
  • Handle: RePEc:plo:pone00:0184412
    DOI: 10.1371/journal.pone.0184412
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