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Increased microcirculatory heterogeneity in patients with obstructive sleep apnea

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  • Lukas Ruzek
  • Karolina Svobodova
  • Lyle J Olson
  • Ondrej Ludka
  • Ivan Cundrle Jr.

Abstract

Introduction: Obstructive sleep apnea (OSA) is the most common form of sleep disordered breathing and has been associated with major cardiovascular comorbidities. We hypothesized that the microcirculation is impaired in patients with OSA and that the magnitude of impairment correlates to OSA severity. Methods: Subjects were consecutive patients scheduled for routine diagnostic polysomnography (PSG). OSA was defined by paradoxical rib cage movements together with abdominal excursions and by the apnea-hypopnea index (AHI) (events/hour; no apnea AHI

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  • Lukas Ruzek & Karolina Svobodova & Lyle J Olson & Ondrej Ludka & Ivan Cundrle Jr., 2017. "Increased microcirculatory heterogeneity in patients with obstructive sleep apnea," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-10, September.
    • Handle: RePEc:plo:pone00:0184291
    DOI: 10.1371/journal.pone.0184291
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