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A Higher Proportion of Metabolic Syndrome in Chinese Subjects with Sleep-Disordered Breathing: A Case-Control Study Based on Electrocardiogram-Derived Sleep Analysis

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  • Ping-Huei Tseng
  • Pei-Lin Lee
  • Wei-Chung Hsu
  • Yan Ma
  • Yi-Chia Lee
  • Han-Mo Chiu
  • Yi-Lwun Ho
  • Ming-Fong Chen
  • Ming-Shiang Wu
  • Chung-Kang Peng

Abstract

Objective: The prevalence of metabolic syndrome (MS) has increased rapidly in Taiwan and worldwide. We aim to determine the association between sleep-disordered breathing (SDB) and MS in a Chinese general population. Methods: This case-control study recruited subjects who have undergone a prospective electrocardiogram-based cardiopulmonary coupling (CPC) sleep spectrogram as part of the periodic health check-ups at the National Taiwan University Hospital. Comprehensive anthropometrics, blood biochemistry, prevalence of MS and its individual components were compared with Bonferroni correction between 40 subjects with SDB, defined as the CPC-derived apnea–hypopnea index (CPC-AHI) >5 event/hour and 80 age- and sex-matched controls, defined as CPC-AHI

Suggested Citation

  • Ping-Huei Tseng & Pei-Lin Lee & Wei-Chung Hsu & Yan Ma & Yi-Chia Lee & Han-Mo Chiu & Yi-Lwun Ho & Ming-Fong Chen & Ming-Shiang Wu & Chung-Kang Peng, 2017. "A Higher Proportion of Metabolic Syndrome in Chinese Subjects with Sleep-Disordered Breathing: A Case-Control Study Based on Electrocardiogram-Derived Sleep Analysis," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-13, January.
    • Handle: RePEc:plo:pone00:0169394
    DOI: 10.1371/journal.pone.0169394
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