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The C-Reactive Protein to Albumin Ratio as a Predictor of Severe Side Effects of Adjuvant Chemotherapy in Stage III Colorectal Cancer Patients

Author

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  • Tetsuro Tominaga
  • Takashi Nonaka
  • Yorihisa Sumida
  • Shigekazu Hidaka
  • Terumitsu Sawai
  • Takeshi Nagayasu

Abstract

Background/Aims: Adjuvant chemotherapy (AC) has been reported to improve the prognosis for patients with Stage III colorectal cancer (CRC). However, some patients experience severe side effects and must stop AC. The C-reactive protein (CRP) to albumin ratio (CAR) is a novel inflammation-based score that could reflect the patient’s general condition. The aim of this study was to evaluate the predictive value of the CAR for side effects of AC in CRC. Methods: A total of 136 CRC patients who received AC were retrospectively analyzed. The patients were subdivided into two groups by the CAR level (CAR ≥0.1, n = 30; CD

Suggested Citation

  • Tetsuro Tominaga & Takashi Nonaka & Yorihisa Sumida & Shigekazu Hidaka & Terumitsu Sawai & Takeshi Nagayasu, 2016. "The C-Reactive Protein to Albumin Ratio as a Predictor of Severe Side Effects of Adjuvant Chemotherapy in Stage III Colorectal Cancer Patients," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-11, December.
    • Handle: RePEc:plo:pone00:0167967
    DOI: 10.1371/journal.pone.0167967
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