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Choice of High-Dose Intravenous Iron Preparation Determines Hypophosphatemia Risk

Author

Listed:
  • Benedikt Schaefer
  • Philipp Würtinger
  • Armin Finkenstedt
  • Vickie Braithwaite
  • André Viveiros
  • Maria Effenberger
  • Irene Sulzbacher
  • Alexander Moschen
  • Andrea Griesmacher
  • Herbert Tilg
  • Wolfgang Vogel
  • Heinz Zoller

Abstract

Background: Ferric carboxymaltose (FCM) and iron isomaltoside 1000 (IIM) are increasingly used because they allow correction of severe iron deficiency in a single infusion. A transient decrease in serum phosphate concentrations is a frequent side effect of FCM. Aim: To characterize this adverse event and search for its predictors in a gastroenterology clinic patient cohort. Methods: Electronic medical records of patients attending the University Hospital of Innsbruck were searched for the keywords ferric carboxymaltose or iron isomaltoside. Eighty-one patients with documented administration of FCM or IIM with plasma phosphate concentrations before and after treatment were included. Results: The prevalence of hypophosphatemia (

Suggested Citation

  • Benedikt Schaefer & Philipp Würtinger & Armin Finkenstedt & Vickie Braithwaite & André Viveiros & Maria Effenberger & Irene Sulzbacher & Alexander Moschen & Andrea Griesmacher & Herbert Tilg & Wolfgan, 2016. "Choice of High-Dose Intravenous Iron Preparation Determines Hypophosphatemia Risk," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-11, December.
    • Handle: RePEc:plo:pone00:0167146
    DOI: 10.1371/journal.pone.0167146
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