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Role of Platelet Parameters on Neovascular Glaucoma: A Retrospective Case-Control Study in China

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  • Shengjie Li
  • Wenjun Cao
  • Xinghuai Sun

Abstract

Purpose: Retinal vein occlusion (RVO) and diabetic retinopathy (DR) are two major sight-threatening diseases which may lead to neovascular glaucoma (NVG). The aim of this study was to explore the association between platelet parameters and NVG. Methods: A total of 185 subjects were enrolled for the study from January, 2012 to December, 2015 at the Eye-ENT Hospital of Fudan University. Patients include those with NVG secondary to RVO (RVO group, n = 38), patients with NVG secondary to DR (DR group, n = 47), diabetics mellitus without retinopathy (DM group, n = 52), and healthy individuals (control group, n = 48). A complete ophthalmological examination including visual field examination, A-scan ultrasound, Fundus photography, and measurement of platelet parameters were performed for NVG subjects. Results: There was no statistical difference in the mean age and gender among the RVO, DR, and control groups (p>0.05). The mean level of platelet distribution width (PDW) was higher (p

Suggested Citation

  • Shengjie Li & Wenjun Cao & Xinghuai Sun, 2016. "Role of Platelet Parameters on Neovascular Glaucoma: A Retrospective Case-Control Study in China," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-11, December.
    • Handle: RePEc:plo:pone00:0166893
    DOI: 10.1371/journal.pone.0166893
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    1. Tomomi Higashide & Shinji Ohkubo & Kazuhisa Sugiyama, 2015. "Long-Term Outcomes and Prognostic Factors of Trabeculectomy following Intraocular Bevacizumab Injection for Neovascular Glaucoma," PLOS ONE, Public Library of Science, vol. 10(8), pages 1-15, August.
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