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Rapid Syphilis Testing Is Cost-Effective Even in Low-Prevalence Settings: The CISNE-PERU Experience

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Listed:
  • Patricia Mallma
  • Patricia Garcia
  • Cesar Carcamo
  • Sergio Torres-Rueda
  • Rosanna Peeling
  • David Mabey
  • Fern Terris-Prestholt

Abstract

Studies have addressed cost-effectiveness of syphilis testing of pregnant women in high-prevalence settings. This study compares costs of rapid syphilis testing (RST) with laboratory-based rapid plasma reagin (RPR) tests in low-prevalence settings in Peru. The RST was introduced in a tertiary-level maternity hospital and in the Ventanilla Network of primary health centers, where syphilis prevalence is approximately 1%. The costs per woman tested and treated with RST at the hospital were $2.70 and $369 respectively compared with $3.60 and $740 for RPR. For the Ventanilla Network the costs per woman tested and treated with RST were $3.19 and $295 respectively compared with $5.55 and $1454 for RPR. The cost per DALY averted using RST was $46 vs. $109 for RPR. RST showed lower costs compared to the WHO standard costs per DALY ($64). Findings suggest syphilis screening with RST is cost-effective in low-prevalence settings.

Suggested Citation

  • Patricia Mallma & Patricia Garcia & Cesar Carcamo & Sergio Torres-Rueda & Rosanna Peeling & David Mabey & Fern Terris-Prestholt, 2016. "Rapid Syphilis Testing Is Cost-Effective Even in Low-Prevalence Settings: The CISNE-PERU Experience," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-11, March.
  • Handle: RePEc:plo:pone00:0149568
    DOI: 10.1371/journal.pone.0149568
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    References listed on IDEAS

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    1. Bruce A Larson & Deophine Lembela-Bwalya & Rachael Bonawitz & Emily E Hammond & Donald M Thea & Julie Herlihy, 2014. "Finding a Needle in the Haystack: The Costs and Cost-Effectiveness of Syphilis Diagnosis and Treatment during Pregnancy to Prevent Congenital Syphilis in Kalomo District of Zambia," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-17, December.
    2. Yalda Jafari & Rosanna W Peeling & Sushmita Shivkumar & Christiane Claessens & Lawrence Joseph & Nitika Pant Pai, 2013. "Are Treponema pallidum Specific Rapid and Point-of-Care Tests for Syphilis Accurate Enough for Screening in Resource Limited Settings? Evidence from a Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(2), pages 1-8, February.
    3. Andreas Kuznik & Mohammed Lamorde & Agnes Nyabigambo & Yukari C Manabe, 2013. "Antenatal Syphilis Screening Using Point-of-Care Testing in Sub-Saharan African Countries: A Cost-Effectiveness Analysis," PLOS Medicine, Public Library of Science, vol. 10(11), pages 1-15, November.
    4. Bruce R Schackman & Christopher P Neukermans & Sandy N Nerette Fontain & Claudine Nolte & Patrice Joseph & Jean W Pape & Daniel W Fitzgerald, 2007. "Cost-Effectiveness of Rapid Syphilis Screening in Prenatal HIV Testing Programs in Haiti," PLOS Medicine, Public Library of Science, vol. 4(5), pages 1-11, May.
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