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Clinical Correlates of Mass Effect in Autosomal Dominant Polycystic Kidney Disease

Author

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  • Hyunsuk Kim
  • Hayne Cho Park
  • Hyunjin Ryu
  • Kiwon Kim
  • Hyo Sang Kim
  • Kook-Hwan Oh
  • Su Jong Yu
  • Jin Wook Chung
  • Jeong Yeon Cho
  • Seung Hyup Kim
  • Hae Il Cheong
  • Kyubeck Lee
  • Jong Hoon Park
  • York Pei
  • Young-Hwan Hwang
  • Curie Ahn

Abstract

Mass effect from polycystic kidney and liver enlargement can result in significant clinical complications and symptoms in autosomal dominant polycystic kidney disease (ADPKD). In this single-center study, we examined the correlation of height-adjusted total liver volume (htTLV) and total kidney volume (htTKV) by CT imaging with hepatic complications (n = 461) and abdominal symptoms (n = 253) in patients with ADPKD. “Mass-effect” complications were assessed by review of medical records and abdominal symptoms, by a standardized research questionnaire. Overall, 91.8% of patients had 4 or more liver cysts on CT scans. Polycystic liver disease (PLD) was classified as none or mild (htTLV

Suggested Citation

  • Hyunsuk Kim & Hayne Cho Park & Hyunjin Ryu & Kiwon Kim & Hyo Sang Kim & Kook-Hwan Oh & Su Jong Yu & Jin Wook Chung & Jeong Yeon Cho & Seung Hyup Kim & Hae Il Cheong & Kyubeck Lee & Jong Hoon Park & Yo, 2015. "Clinical Correlates of Mass Effect in Autosomal Dominant Polycystic Kidney Disease," PLOS ONE, Public Library of Science, vol. 10(12), pages 1-14, December.
  • Handle: RePEc:plo:pone00:0144526
    DOI: 10.1371/journal.pone.0144526
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