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Visualizing Risk Prediction Models

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  • Vanya Van Belle
  • Ben Van Calster

Abstract

Objective: Risk prediction models can assist clinicians in making decisions. To boost the uptake of these models in clinical practice, it is important that end-users understand how the model works and can efficiently communicate its results. We introduce novel methods for interpretable model visualization. Methods: The proposed visualization techniques are applied to two prediction models from the Framingham Heart Study for the prediction of intermittent claudication and stroke after atrial fibrillation. We represent models using color bars, and visualize the risk estimation process for a specific patient using patient-specific contribution charts. Results: The color-based model representations provide users with an attractive tool to instantly gauge the relative importance of the predictors. The patient-specific representations allow users to understand the relative contribution of each predictor to the patient’s estimated risk, potentially providing insightful information on which to base further patient management. Extensions towards non-linear models and interactions are illustrated on an artificial dataset. Conclusion: The proposed methods summarize risk prediction models and risk predictions for specific patients in an alternative way. These representations may facilitate communication between clinicians and patients.

Suggested Citation

  • Vanya Van Belle & Ben Van Calster, 2015. "Visualizing Risk Prediction Models," PLOS ONE, Public Library of Science, vol. 10(7), pages 1-16, July.
  • Handle: RePEc:plo:pone00:0132614
    DOI: 10.1371/journal.pone.0132614
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    1. Margaret Pepe & Holly Janes & Gary Longton & Wendy Leisenring & Polly Newcomb, 2004. "Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic or Prognostic Marker," UW Biostatistics Working Paper Series 1035, Berkeley Electronic Press.
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    1. Amirhossein Jalali & Alberto Alvarez-Iglesias & Davood Roshan & John Newell, 2019. "Visualising statistical models using dynamic nomograms," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-15, November.
    2. Yaniv Hanoch & Jonathan Rolison & Alexandra M. Freund, 2019. "Reaping the Benefits and Avoiding the Risks: Unrealistic Optimism in the Health Domain," Risk Analysis, John Wiley & Sons, vol. 39(4), pages 792-804, April.
    3. Alexander Caicedo & Carolina Varon & Sabine Van Huffel & Johan A K Suykens, 2019. "Functional form estimation using oblique projection matrices for LS-SVM regression models," PLOS ONE, Public Library of Science, vol. 14(6), pages 1-21, June.

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