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Longitudinal Associations between Adolescent Psychotic Experiences and Depressive Symptoms

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  • Sarah A Sullivan
  • Nicola Wiles
  • Daphne Kounali
  • Glyn Lewis
  • Jon Heron
  • Mary Cannon
  • Liam Mahedy
  • Peter B Jones
  • Jan Stochl
  • Stan Zammit

Abstract

Background: Psychotic experiences are prevalent in community samples and are highly correlated with depressive symptoms. This study aimed to investigate the longitudinal associations between psychotic experiences and depressive symptoms between adolescence and young adulthood. Method: Prospective cohort study with a 6 year follow-up in a community sample of 7632 adolescents and young adults. Depressive symptoms were assessed with the Short Moods and Feelings Questionnaire and psychotic experiences with a semi-structured clinical interview at 12 and 18 years. Longitudinal and cross-sectional associations were investigated with regression and structural equation models. Results: Depressive symptoms and psychotic experiences were associated at each time-point (12 years r = 0.486 [95% CI 0.457, 0.515]; 18 years r = 0.286 [95% CI 0.233, 0.339]) and there were longitudinal within-phenotype associations (depressive symptoms r = 0.252 [95% CI 0.205, 0.299]; psychotic experiences r = 0.662 [95% CI 0.595, 0.729]). There was an across-phenotype association between psychotic experiences at 12 and depressive symptoms at 18 r = 0.139 [95% CI 0.086, 0.192; p

Suggested Citation

  • Sarah A Sullivan & Nicola Wiles & Daphne Kounali & Glyn Lewis & Jon Heron & Mary Cannon & Liam Mahedy & Peter B Jones & Jan Stochl & Stan Zammit, 2014. "Longitudinal Associations between Adolescent Psychotic Experiences and Depressive Symptoms," PLOS ONE, Public Library of Science, vol. 9(8), pages 1-7, August.
    • Handle: RePEc:plo:pone00:0105758
    DOI: 10.1371/journal.pone.0105758
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