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Predictors of Mortality among Patients Enrolled on Antiretroviral Therapy in Aksum Hospital, Northern Ethiopia: A Retrospective Cohort Study

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  • Kidane Tadesse
  • Fisaha Haile
  • Neway Hiruy

Abstract

Background: Since launching of antiretroviral (ART) treatment, the numbers of patients enrolled in to ART are increasing in many developing countries. But many studies done across Africa including Ethiopia on antiretroviral therapy programs have shown higher mortality at the first six months of treatment initiation. But the factors associated with this high mortality are poorly characterized. So this study aims to determine mortality and identify predictors of it among patients on ART. Methods: Retrospective cohort study was employed among a total of 520 records of patients who were enrolled on antiretroviral therapy in Aksum hospital from September 2006 to August 2011. Baseline patient records were extracted from electronic and paper based medical records database and analysed using Kaplan Meier survival and Cox proportional hazard model to identify the independent predictors of mortality of patients on ART. Results: A total of 46 (8.85%) deaths was observed giving an overall mortality rate of 3.2 per 100 person-years. The independent predictor of mortality identified for this cohort were haemoglobin level

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  • Kidane Tadesse & Fisaha Haile & Neway Hiruy, 2014. "Predictors of Mortality among Patients Enrolled on Antiretroviral Therapy in Aksum Hospital, Northern Ethiopia: A Retrospective Cohort Study," PLOS ONE, Public Library of Science, vol. 9(1), pages 1-6, January.
    • Handle: RePEc:plo:pone00:0087392
    DOI: 10.1371/journal.pone.0087392
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    Cited by:

    1. Dinberu Seyoum & Jean-Marie Degryse & Yehenew Getachew Kifle & Ayele Taye & Mulualem Tadesse & Belay Birlie & Akalu Banbeta & Angel Rosas-Aguirre & Luc Duchateau & Niko Speybroeck, 2017. "Risk Factors for Mortality among Adult HIV/AIDS Patients Following Antiretroviral Therapy in Southwestern Ethiopia: An Assessment through Survival Models," IJERPH, MDPI, vol. 14(3), pages 1-12, March.
    2. Hailay Abrha Gesesew & Paul Ward & Kifle Woldemichael & Lillian Mwanri, 2018. "Early mortality among children and adults in antiretroviral therapy programs in Southwest Ethiopia, 2003–15," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-17, June.

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