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Clinical Significance of Asthma Clusters by Longitudinal Analysis in Korean Asthma Cohort

Author

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  • So Young Park
  • Seunghee Baek
  • Sujeong Kim
  • Sun-young Yoon
  • Hyouk-Soo Kwon
  • Yoon-Seok Chang
  • You Sook Cho
  • An-Soo Jang
  • Jung Won Park
  • Dong-Ho Nahm
  • Ho-Joo Yoon
  • Sang-Heon Cho
  • Young-Joo Cho
  • ByoungWhui Choi
  • Hee-Bom Moon
  • Tae-Bum Kim
  • for the COREA Study Group

Abstract

Background: We have previously identified four distinct groups of asthma patients in Korean cohorts using cluster analysis: (A) smoking asthma, (B) severe obstructive asthma, (C) early-onset atopic asthma, and (D) late-onset mild asthma. Methods and Results: A longitudinal analysis of each cluster in a Korean adult asthma cohort was performed to investigate the clinical significance of asthma clusters over 12 months. Conclusion: Our asthma clusters had clinical significance with consistency among clusters over 12 months. These distinctive phenotypes may be useful in classifying asthma in real practice.

Suggested Citation

  • So Young Park & Seunghee Baek & Sujeong Kim & Sun-young Yoon & Hyouk-Soo Kwon & Yoon-Seok Chang & You Sook Cho & An-Soo Jang & Jung Won Park & Dong-Ho Nahm & Ho-Joo Yoon & Sang-Heon Cho & Young-Joo Ch, 2013. "Clinical Significance of Asthma Clusters by Longitudinal Analysis in Korean Asthma Cohort," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-6, December.
    • Handle: RePEc:plo:pone00:0083540
    DOI: 10.1371/journal.pone.0083540
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