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Longitudinal Assessment of Optical Quality and Intraocular Scattering Using the Double-Pass Instrument in Normal Eyes and Eyes with Short Tear Breakup Time

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  • Hidenaga Kobashi
  • Kazutaka Kamiya
  • Kyohei Yanome
  • Akihito Igarashi
  • Kimiya Shimizu

Abstract

Purpose: To assess the longitudinal changes in optical quality including intraocular scattering in normal eyes and eyes with short tear breakup time (TBUT). Methods: We prospectively examined twenty eyes of 20 healthy subjects, and age-matched twenty eyes of 20 short TBUT subjects. The modulation transfer function (MTF) cutoff frequency, the Strehl ratio, and the objective scattering index (OSI) were quantitatively assessed using an Optical Quality Analysis System. We investigated the changes in these variables measured consecutively at the initial examination, 5, and 10 seconds without blinking. We also compared these variables in eyes with short TBUT with those in normal eyes. Results: No significant differences in the MTF cutoff frequency, Strehl ratio, or OSI were detected over a 10-second period in normal eyes. These variables also became significantly degraded even over a 5-second period in eyes with short TBUT (p

Suggested Citation

  • Hidenaga Kobashi & Kazutaka Kamiya & Kyohei Yanome & Akihito Igarashi & Kimiya Shimizu, 2013. "Longitudinal Assessment of Optical Quality and Intraocular Scattering Using the Double-Pass Instrument in Normal Eyes and Eyes with Short Tear Breakup Time," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-6, December.
    • Handle: RePEc:plo:pone00:0082427
    DOI: 10.1371/journal.pone.0082427
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