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Reference Values of Impulse Oscillometric Lung Function Indices in Adults of Advanced Age

Author

Listed:
  • Holger Schulz
  • Claudia Flexeder
  • Jürgen Behr
  • Margit Heier
  • Rolf Holle
  • Rudolf M Huber
  • Rudolf A Jörres
  • Dennis Nowak
  • Annette Peters
  • H-Erich Wichmann
  • Joachim Heinrich
  • Stefan Karrasch
  • the KORA Study Group

Abstract

Background: Impulse oscillometry (IOS) is a non-demanding lung function test. Its diagnostic use may be particularly useful in patients of advanced age with physical or mental limitations unable to perform spirometry. Only few reference equations are available for Caucasians, none of them covering the old age. Here, we provide reference equations up to advanced age and compare them with currently available equations. Methods: IOS was performed in a population-based sample of 1990 subjects, aged 45–91 years, from KORA cohorts (Augsburg, Germany). From those, 397 never-smoking, lung healthy subjects with normal spirometry were identified and sex-specific quantile regression models with age, height and body weight as predictors for respiratory system impedance, resistance, reactance, and other parameters of IOS applied. Results: Women (n = 243) showed higher resistance values than men (n = 154), while reactance at low frequencies (up to 20 Hz) was lower (p

Suggested Citation

  • Holger Schulz & Claudia Flexeder & Jürgen Behr & Margit Heier & Rolf Holle & Rudolf M Huber & Rudolf A Jörres & Dennis Nowak & Annette Peters & H-Erich Wichmann & Joachim Heinrich & Stefan Karrasch & , 2013. "Reference Values of Impulse Oscillometric Lung Function Indices in Adults of Advanced Age," PLOS ONE, Public Library of Science, vol. 8(5), pages 1-10, May.
  • Handle: RePEc:plo:pone00:0063366
    DOI: 10.1371/journal.pone.0063366
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