IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0057848.html
   My bibliography  Save this article

The SHOCT Domain: A Widespread Domain Under-Represented in Model Organisms

Author

Listed:
  • Ruth Y Eberhardt
  • S Josefin Bartholdson
  • Marco Punta
  • Alex Bateman

Abstract

We have identified a new protein domain, which we have named the SHOCT domain (Short C-terminal domain). This domain is widespread in bacteria with over a thousand examples. But we found it is missing from the most commonly studied model organisms, despite being present in closely related species. It's predominantly C-terminal location, co-occurrence with numerous other domains and short size is reminiscent of the Gram-positive anchor motif, however it is present in a much wider range of species. We suggest several hypotheses about the function of SHOCT, including oligomerisation and nucleic acid binding. Our initial experiments do not support its role as an oligomerisation domain.

Suggested Citation

  • Ruth Y Eberhardt & S Josefin Bartholdson & Marco Punta & Alex Bateman, 2013. "The SHOCT Domain: A Widespread Domain Under-Represented in Model Organisms," PLOS ONE, Public Library of Science, vol. 8(2), pages 1-7, February.
    • Handle: RePEc:plo:pone00:0057848
    DOI: 10.1371/journal.pone.0057848
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057848
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0057848&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0057848?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0057848. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.