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Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Author

Listed:
  • Sarah L Lambton
  • Adrian D Colloff
  • Richard P Smith
  • George L Caldow
  • Sandra F E Scholes
  • Kim Willoughby
  • Fiona Howie
  • Johanne Ellis-Iversen
  • Graham David
  • Alasdair J C Cook
  • Andrew Holliman

Abstract

Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p

Suggested Citation

  • Sarah L Lambton & Adrian D Colloff & Richard P Smith & George L Caldow & Sandra F E Scholes & Kim Willoughby & Fiona Howie & Johanne Ellis-Iversen & Graham David & Alasdair J C Cook & Andrew Holliman, 2012. "Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study," PLOS ONE, Public Library of Science, vol. 7(5), pages 1-7, May.
  • Handle: RePEc:plo:pone00:0034183
    DOI: 10.1371/journal.pone.0034183
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