In many applications, researchers are interested in estimating the mean of a multivariate normal random vector whose components are subject to order restrictions. Various authors have demonstrated that the likelihood-based methodology may perform poorly under certain conditions for such problems. The problem is much harder when the underlying covariance matrix is nondiagonal. In this paper a simple iterative algorithm is introduced that can be used for estimating the mean of a multivariate normal population when the components are subject to any order restriction. The proposed methodology is illustrated through an application to human reproductive hormone data. Copyright 2005, Oxford University Press.
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Article provided by Oxford University Press for Biometrika Trust in its journal Biometrika.
Volume (Year): 92 (2005) Issue (Month): 3 (September) Pages: 703-715 Download reference. The following formats are available: HTML
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