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Quantitative microbiome profiling links gut community variation to microbial load

Author

Listed:
  • Doris Vandeputte

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology
    Research Group of Microbiology, Vrije Universiteit Brussel)

  • Gunter Kathagen

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • Kevin D’hoe

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology
    Research Group of Microbiology, Vrije Universiteit Brussel)

  • Sara Vieira-Silva

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • Mireia Valles-Colomer

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • João Sabino

    (Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven)

  • Jun Wang

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • Raul Y. Tito

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology
    Research Group of Microbiology, Vrije Universiteit Brussel)

  • Lindsey De Commer

    (KU Leuven – University of Leuven, Rega Institute)

  • Youssef Darzi

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • Séverine Vermeire

    (Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven)

  • Gwen Falony

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

  • Jeroen Raes

    (KU Leuven – University of Leuven, Rega Institute
    VIB, Center for Microbiology)

Abstract

Quantitive microbiome profiling reveals that total microbial load is an important determinant of enterotypes and may be a key driver of microbiota alterations in patients with Crohn’s disease.

Suggested Citation

  • Doris Vandeputte & Gunter Kathagen & Kevin D’hoe & Sara Vieira-Silva & Mireia Valles-Colomer & João Sabino & Jun Wang & Raul Y. Tito & Lindsey De Commer & Youssef Darzi & Séverine Vermeire & Gwen Falo, 2017. "Quantitative microbiome profiling links gut community variation to microbial load," Nature, Nature, vol. 551(7681), pages 507-511, November.
    • Handle: RePEc:nat:nature:v:551:y:2017:i:7681:d:10.1038_nature24460
    DOI: 10.1038/nature24460
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    Citations

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    Cited by:

    1. Karen D. Corbin & Elvis A. Carnero & Blake Dirks & Daria Igudesman & Fanchao Yi & Andrew Marcus & Taylor L. Davis & Richard E. Pratley & Bruce E. Rittmann & Rosa Krajmalnik-Brown & Steven R. Smith, 2023. "Host-diet-gut microbiome interactions influence human energy balance: a randomized clinical trial," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    2. Petros Andrikopoulos & Judith Aron-Wisnewsky & Rima Chakaroun & Antonis Myridakis & Sofia K. Forslund & Trine Nielsen & Solia Adriouch & Bridget Holmes & Julien Chilloux & Sara Vieira-Silva & Gwen Fal, 2023. "Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
    3. Joonatan Palmu & Leo Lahti & Teemu Niiranen, 2021. "Targeting Gut Microbiota to Treat Hypertension: A Systematic Review," IJERPH, MDPI, vol. 18(3), pages 1-14, January.
    4. Luis Gerardo Hernández García, 2022. "Transport equipment network analysis: the value-added contribution," Journal of Economic Structures, Springer;Pan-Pacific Association of Input-Output Studies (PAPAIOS), vol. 11(1), pages 1-25, December.
    5. Brian D. Williamson & James P. Hughes & Amy D. Willis, 2022. "A multiview model for relative and absolute microbial abundances," Biometrics, The International Biometric Society, vol. 78(3), pages 1181-1194, September.

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