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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

Author

Listed:
  • Angela Bononi

    (University of Hawaii Cancer Center, University of Hawaii)

  • Carlotta Giorgi

    (Surgery and Experimental Medicine, University of Ferrara)

  • Simone Patergnani

    (Surgery and Experimental Medicine, University of Ferrara)

  • David Larson

    (University of Hawaii Cancer Center, University of Hawaii)

  • Kaitlyn Verbruggen

    (University of Hawaii Cancer Center, University of Hawaii)

  • Mika Tanji

    (University of Hawaii Cancer Center, University of Hawaii)

  • Laura Pellegrini

    (University of Hawaii Cancer Center, University of Hawaii)

  • Valentina Signorato

    (University of Hawaii Cancer Center, University of Hawaii
    Surgery and Experimental Medicine, University of Ferrara)

  • Federica Olivetto

    (University of Hawaii Cancer Center, University of Hawaii
    Surgery and Experimental Medicine, University of Ferrara)

  • Sandra Pastorino

    (University of Hawaii Cancer Center, University of Hawaii)

  • Masaki Nasu

    (University of Hawaii Cancer Center, University of Hawaii)

  • Andrea Napolitano

    (University of Hawaii Cancer Center, University of Hawaii)

  • Giovanni Gaudino

    (University of Hawaii Cancer Center, University of Hawaii)

  • Paul Morris

    (University of Hawaii Cancer Center, University of Hawaii)

  • Greg Sakamoto

    (University of Hawaii Cancer Center, University of Hawaii)

  • Laura K. Ferris

    (University of Pittsburgh Medical Center)

  • Alberto Danese

    (Surgery and Experimental Medicine, University of Ferrara)

  • Andrea Raimondi

    (Experimental Imaging Center, San Raffaele Scientific Institute Milano)

  • Carlo Tacchetti

    (Experimental Imaging Center, San Raffaele Scientific Institute Milano
    University of Genova)

  • Shafi Kuchay

    (Cancer Center, New York University)

  • Harvey I. Pass

    (Cancer Center, New York University)

  • El Bachir Affar

    (Maisonneuve-Rosemont Hospital Research Center, University of Montréal)

  • Haining Yang

    (University of Hawaii Cancer Center, University of Hawaii)

  • Paolo Pinton

    (Surgery and Experimental Medicine, University of Ferrara)

  • Michele Carbone

    (University of Hawaii Cancer Center, University of Hawaii)

Abstract

BRCA1-associated protein 1 (BAP1) regulates calcium flux in the endoplasmic reticulum to facilitate the execution of apoptosis, unveiling a new facet of the role of BAP1 as an environmental tumour suppressor.

Suggested Citation

  • Angela Bononi & Carlotta Giorgi & Simone Patergnani & David Larson & Kaitlyn Verbruggen & Mika Tanji & Laura Pellegrini & Valentina Signorato & Federica Olivetto & Sandra Pastorino & Masaki Nasu & And, 2017. "BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation," Nature, Nature, vol. 546(7659), pages 549-553, June.
    • Handle: RePEc:nat:nature:v:546:y:2017:i:7659:d:10.1038_nature22798
    DOI: 10.1038/nature22798
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    Cited by:

    1. Nidhi Rohatgi & Wei Zou & Yongjia Li & Kevin Cho & Patrick L. Collins & Eric Tycksen & Gaurav Pandey & Carl J. DeSelm & Gary J. Patti & Anwesha Dey & Steven L. Teitelbaum, 2023. "BAP1 promotes osteoclast function by metabolic reprogramming," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Shuang-Shuang Zhang & Shi Zhou & Zachary J. Crowley-McHattan & Rui-Yuan Wang & Jun-Ping Li, 2021. "A Review of the Role of Endo/Sarcoplasmic Reticulum-Mitochondria Ca 2+ Transport in Diseases and Skeletal Muscle Function," IJERPH, MDPI, vol. 18(8), pages 1-12, April.

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