IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v539y2016i7628d10.1038_nature20123.html
   My bibliography  Save this article

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

Author

Listed:
  • Itay Tirosh

    (Broad Institute of Harvard and MIT)

  • Andrew S. Venteicher

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School)

  • Christine Hebert

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Leah E. Escalante

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Anoop P. Patel

    (Massachusetts General Hospital and Harvard Medical School)

  • Keren Yizhak

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Jonathan M. Fisher

    (Broad Institute of Harvard and MIT)

  • Christopher Rodman

    (Broad Institute of Harvard and MIT)

  • Christopher Mount

    (Neurosurgery, Pediatrics and Pathology, Stanford University School of Medicine)

  • Mariella G. Filbin

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School
    Dana-Farber Cancer Institute and Children’s Hospital Cancer Center)

  • Cyril Neftel

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Niyati Desai

    (Massachusetts General Hospital and Harvard Medical School)

  • Jackson Nyman

    (Broad Institute of Harvard and MIT)

  • Benjamin Izar

    (Broad Institute of Harvard and MIT)

  • Christina C. Luo

    (Massachusetts General Hospital and Harvard Medical School)

  • Joshua M. Francis

    (Broad Institute of Harvard and MIT
    Dana-Farber Cancer Institute)

  • Aanand A. Patel

    (Massachusetts General Hospital and Harvard Medical School)

  • Maristela L. Onozato

    (Massachusetts General Hospital and Harvard Medical School)

  • Nicolo Riggi

    (Massachusetts General Hospital and Harvard Medical School)

  • Kenneth J. Livak

    (Broad Institute of Harvard and MIT)

  • Dave Gennert

    (Broad Institute of Harvard and MIT)

  • Rahul Satija

    (Broad Institute of Harvard and MIT)

  • Brian V. Nahed

    (Massachusetts General Hospital and Harvard Medical School)

  • William T. Curry

    (Massachusetts General Hospital and Harvard Medical School)

  • Robert L. Martuza

    (Massachusetts General Hospital and Harvard Medical School)

  • Ravindra Mylvaganam

    (Massachusetts General Hospital and Harvard Medical School)

  • A. John Iafrate

    (Massachusetts General Hospital and Harvard Medical School)

  • Matthew P. Frosch

    (Massachusetts General Hospital and Harvard Medical School)

  • Todd R. Golub

    (Broad Institute of Harvard and MIT
    Dana-Farber Cancer Institute and Children’s Hospital Cancer Center
    Howard Hughes Medical Institute, Koch Institute, MIT)

  • Miguel N. Rivera

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Gad Getz

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • Orit Rozenblatt-Rosen

    (Broad Institute of Harvard and MIT)

  • Daniel P. Cahill

    (Massachusetts General Hospital and Harvard Medical School)

  • Michelle Monje

    (Neurosurgery, Pediatrics and Pathology, Stanford University School of Medicine)

  • Bradley E. Bernstein

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

  • David N. Louis

    (Massachusetts General Hospital and Harvard Medical School)

  • Aviv Regev

    (Broad Institute of Harvard and MIT
    Howard Hughes Medical Institute, Koch Institute, MIT)

  • Mario L. Suvà

    (Broad Institute of Harvard and MIT
    Massachusetts General Hospital and Harvard Medical School)

Abstract

A single sentence summarizing your paper (websum), which will appear online on the table of contents and in e-alerts, has been provided below. Please check this sentence for accuracy and appropriate emphasis.

Suggested Citation

  • Itay Tirosh & Andrew S. Venteicher & Christine Hebert & Leah E. Escalante & Anoop P. Patel & Keren Yizhak & Jonathan M. Fisher & Christopher Rodman & Christopher Mount & Mariella G. Filbin & Cyril Nef, 2016. "Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma," Nature, Nature, vol. 539(7628), pages 309-313, November.
    • Handle: RePEc:nat:nature:v:539:y:2016:i:7628:d:10.1038_nature20123
    DOI: 10.1038/nature20123
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature20123
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature20123?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Wei Cheng & Hao-Long Li & Shao-Yan Xi & Xiao-Feng Zhang & Yun Zhu & Le Xing & Yan-Xuan Mo & Mei-Mei Li & Fan-En Kong & Wen-Jie Zhu & Xiao-Gang Chen & Hui-Qing Cui & Zhi-Ming Cao & Yuan-Feng Gong & Yun, 2021. "Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    2. Jeff DeMartino & Michael T. Meister & Lindy L. Visser & Mariël Brok & Marian J. A. Groot Koerkamp & Amber K. L. Wezenaar & Laura S. Hiemcke-Jiwa & Terezinha Souza & Johannes H. M. Merks & Anne C. Rios, 2023. "Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    3. Akram A. Hamed & Daniel J. Kunz & Ibrahim El-Hamamy & Quang M. Trinh & Omar D. Subedar & Laura M. Richards & Warren Foltz & Garrett Bullivant & Matthaeus Ware & Maria C. Vladoiu & Jiao Zhang & Antony , 2022. "A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    4. Yumin Liu & Linjuan Shi & Yifan Chen & Sifan Luo & Yuehang Chen & Hongtian Chen & Wenlang Lan & Xun Lu & Zhan Cao & Zehua Ye & Jinping Li & Bo Yu & Elaine Dzierzak & Zhuan Li, 2024. "Autophagy regulates the maturation of hematopoietic precursors in the embryo," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    5. Qianqian Zhang & Sijin Cheng & Yongzhi Wang & Mengdi Wang & Yufeng Lu & Zengqi Wen & Yuxin Ge & Qiang Ma & Youqiao Chen & Yaowu Zhang & Ren Cao & Min Li & Weihao Liu & Bo Wang & Qian Wu & Wenqing Jia , 2021. "Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
    6. Polina Kameneva & Victoria I. Melnikova & Maria Eleni Kastriti & Anastasia Kurtova & Emil Kryukov & Aliia Murtazina & Louis Faure & Irina Poverennaya & Artem V. Artemov & Tatiana S. Kalinina & Nikita , 2022. "Serotonin limits generation of chromaffin cells during adrenal organ development," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
    7. Weilin Pu & Xiao Shi & Pengcheng Yu & Meiying Zhang & Zhiyan Liu & Licheng Tan & Peizhen Han & Yu Wang & Dongmei Ji & Hualei Gan & Wenjun Wei & Zhongwu Lu & Ning Qu & Jiaqian Hu & Xiaohua Hu & Zaili L, 2021. "Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma," Nature Communications, Nature, vol. 12(1), pages 1-18, December.
    8. Hyeon-Jin Kim & Greg Booth & Lauren Saunders & Sanjay Srivatsan & José L. McFaline-Figueroa & Cole Trapnell, 2022. "Nuclear oligo hashing improves differential analysis of single-cell RNA-seq," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    9. Yuanning Zheng & Francisco Carrillo-Perez & Marija Pizurica & Dieter Henrik Heiland & Olivier Gevaert, 2023. "Spatial cellular architecture predicts prognosis in glioblastoma," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    10. Michael J. Geuenich & Dae-won Gong & Kieran R. Campbell, 2024. "The impacts of active and self-supervised learning on efficient annotation of single-cell expression data," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    11. Vidhya M. Ravi & Nicolas Neidert & Paulina Will & Kevin Joseph & Julian P. Maier & Jan Kückelhaus & Lea Vollmer & Jonathan M. Goeldner & Simon P. Behringer & Florian Scherer & Melanie Boerries & Marie, 2022. "T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    12. Alma Andersson & Ludvig Larsson & Linnea Stenbeck & Fredrik Salmén & Anna Ehinger & Sunny Z. Wu & Ghamdan Al-Eryani & Daniel Roden & Alex Swarbrick & Åke Borg & Jonas Frisén & Camilla Engblom & Joakim, 2021. "Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    13. Rana Salam & Alexa Saliou & Franck Bielle & Mathilde Bertrand & Christophe Antoniewski & Catherine Carpentier & Agusti Alentorn & Laurent Capelle & Marc Sanson & Emmanuelle Huillard & Léa Bellenger & , 2023. "Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
    14. Irfete S. Fetahu & Wolfgang Esser-Skala & Rohit Dnyansagar & Samuel Sindelar & Fikret Rifatbegovic & Andrea Bileck & Lukas Skos & Eva Bozsaky & Daria Lazic & Lisa Shaw & Marcus Tötzl & Dora Tarlungean, 2023. "Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    15. Antonio De Falco & Francesca Caruso & Xiao-Dong Su & Antonio Iavarone & Michele Ceccarelli, 2023. "A variational algorithm to detect the clonal copy number substructure of tumors from scRNA-seq data," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    16. Seethalakshmi Hariharan & Benjamin T. Whitfield & Christopher J. Pirozzi & Matthew S. Waitkus & Michael C. Brown & Michelle L. Bowie & David M. Irvin & Kristen Roso & Rebecca Fuller & Janell Hostettle, 2024. "Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    17. Taghreed Hirz & Shenglin Mei & Hirak Sarkar & Youmna Kfoury & Shulin Wu & Bronte M. Verhoeven & Alexander O. Subtelny & Dimitar V. Zlatev & Matthew W. Wszolek & Keyan Salari & Evan Murray & Fei Chen &, 2023. "Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses," Nature Communications, Nature, vol. 14(1), pages 1-20, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:539:y:2016:i:7628:d:10.1038_nature20123. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.