IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v445y2007i7123d10.1038_nature05466.html
   My bibliography  Save this article

Two chemosensory receptors together mediate carbon dioxide detection in Drosophila

Author

Listed:
  • Walton D. Jones

    (The Rockefeller University)

  • Pelin Cayirlioglu

    (University of California)

  • Ilona Grunwald Kadow

    (University of California
    Max-Planck Institute of Neurobiology)

  • Leslie B. Vosshall

    (The Rockefeller University)

Abstract

The scent of man Many insects are equipped with neurons that detect carbon dioxide. The use to which they are put varies according to the insect's ecology: hawk-moths use it as a measure of the quality of datura flowers. Closer to home, mosquitoes and other blood-feeders are attracted to the carbon dioxide emitted by us. Drosophila too has these sensors: two receptors, called Gr21a and Gr63a, have now been identified in the fruit fly. Flies with only one of the two are insensitive to carbon dioxide, but when both genes are expressed the neurons are sensitive to the gas. Similar genes are present in the malaria mosquito, so they may be useful targets for drugs aimed at reducing the ability of mosquitoes to find humans to bite.

Suggested Citation

  • Walton D. Jones & Pelin Cayirlioglu & Ilona Grunwald Kadow & Leslie B. Vosshall, 2007. "Two chemosensory receptors together mediate carbon dioxide detection in Drosophila," Nature, Nature, vol. 445(7123), pages 86-90, January.
    • Handle: RePEc:nat:nature:v:445:y:2007:i:7123:d:10.1038_nature05466
    DOI: 10.1038/nature05466
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature05466
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature05466?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Clement Kent & Reza Azanchi & Ben Smith & Adrienne Chu & Joel Levine, 2007. "A Model-Based Analysis of Chemical and Temporal Patterns of Cuticular Hydrocarbons in Male Drosophila melanogaster," PLOS ONE, Public Library of Science, vol. 2(9), pages 1-21, September.
    2. Johnna Doherty & Amy E Sheehan & Rachel Bradshaw & A Nicole Fox & Tsai-Yi Lu & Marc R Freeman, 2014. "PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury," PLOS Biology, Public Library of Science, vol. 12(11), pages 1-16, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:445:y:2007:i:7123:d:10.1038_nature05466. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.